70362-55-9

Upstream product

• 72-18-4 L-valine 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 5350-57-2 benzophenone hydrazone 

Downstream Products

• 593252-94-9 (S)-2-Benzyloxycarbonylamino-3-methyl-butyric acid (S)-1-benzhydryloxycarbonyl-2-methyl-propyl ester 
• 494870-79-0 (R)-2-allyloxyamino-3-methylbutiryc acid benzhydryl ester 
• 494870-81-4 (R)-3-methyl-2-(3-oxo-3,6-dihydro[1,2]oxazin-2-yl)-butyric acid benzhydryl ester 
• 494870-80-3 (R)-2-(N-acryloyl-N-allyloxyamino)-3-methylbutyric acid benzhydryl ester 
• 593252-98-3 (S)-2-((S)-3-Hydroxy-2,2-dimethyl-oct-7-ynoylamino)-3-methyl-butyric acid (S)-1-[((S)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 593252-95-0 (S)-2-((S)-3-Hydroxy-2,2-dimethyl-oct-7-ynoylamino)-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 593253-00-0 (S)-2-((R)-3-Hydroxy-2,2-dimethyl-oct-7-ynoylamino)-3-methyl-butyric acid (S)-1-[((S)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 593252-99-4 (S)-2-((R)-3-Hydroxy-2,2-dimethyl-oct-7-ynoylamino)-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 593252-97-2 (S)-2-Benzyloxycarbonylamino-3-methyl-butyric acid (S)-1-[((S)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 593252-88-1 (S)-2-Benzyloxycarbonylamino-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 790302-27-1 (S)-2-(Benzyloxycarbonyl-methyl-amino)-3-methyl-butyric acid (S)-2-methyl-1-[(S)-2-methyl-1-(2,2,2-trichloro-ethoxycarbonyl)-propoxycarbonyl]-propyl ester 
• 18668-12-7 2-(N-benzyloxycarbonyl-N-methylamino)-3-methylbutyric acid 1-carboxy-2-methylpropyl ester 

Relevant academic research and scientific papers

The total synthesis and stereochemical revision of yanucamide A

(Matrix presented) The first total synthesis of yanucamide A is reported via amide and ester couplings of the key components. This synthesis has established the configuration at the previously ambiguous 3-position, and also revised the stereochemistry at the 22-position, to give 3S,12S,17S,22S for the natural product.

Stereocontrolled synthesis of onchidins

(Chemical Equation Presented) The first total synthesis of a molecule possessing the stereochemistry proposed for onchidin is described. The structure synthesized appears to be different from that of the marine natural product.