70365-38-7Relevant articles and documents
One-step reductive amidation of nitro arenes: Application in the synthesis of Acetaminophen
Bhattacharya, Apurba,Purohit, Vikram C.,Suarez, Victor,Tichkule, Ritesh,Parmer, Gaurang,Rinaldi, Frank
, p. 1861 - 1864 (2006)
A novel thioacetate mediated one-step reductive acetamidation of aryl nitro compounds was developed and applied to an efficient synthesis of acetaminophen. The reaction also proceeds well without a solvent in the presence of a catalytic amount of surfactant.