70369-46-9

Upstream product

• 18465-50-4 4,6-O-ethylidene-D-glucopyranose 
• 13224-97-0 (1’R)-(-)-4,6-O-ethylidene-D-glucose 
• 70377-89-8 (1'R)-(-)-2,4-O-ethylidene-D-erythrose 

Downstream Products

• 183888-91-7 (2R,4S,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2-methyl-[1,3]dioxan-5-ol 
• 104322-68-1 (2S)-benzyloxy-[(4S)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetaldehyde 
• 104322-71-6 (2S,3R,4R)-4-Benzyloxy-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-(3-methyl-but-2-enyl)-butane-1,3-diol 
• 104322-70-5 (R)-2-[(1R,2R)-2-Benzyloxy-2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-1-hydroxy-ethyl]-5-methyl-hex-4-enethioic acid S-phenyl ester 
• 183888-93-9 ((2R,4S,5R)-5-Benzyloxy-2-methyl-[1,3]dioxan-4-ylmethoxy)-tert-butyl-diphenyl-silane 
• 188925-44-2 (2R,4R,5R)-5-Ethyl-2-methyl-4-trityloxymethyl-[1,3]dioxan-5-ol 
• 188925-35-1 (2R,4S,5R)-5-Ethyl-2-methyl-4-trityloxymethyl-[1,3]dioxan-5-ol 
• 188925-22-6 (2R,4R)-2-Methyl-4-trityloxymethyl-[1,3]dioxan-5-one 
• 188925-12-4 (2R,4S)-2-Methyl-4-trityloxymethyl-[1,3]dioxan-5-one 
• 188925-27-1 (2R,4R,5R)-2,5-Dimethyl-4-trityloxymethyl-[1,3]dioxan-5-ol 
• 188925-30-6 (2R,4S,5R)-2,5-Dimethyl-4-trityloxymethyl-[1,3]dioxan-5-ol 
• 188925-23-7 (2R,4R)-4-Benzyloxymethyl-2-methyl-[1,3]dioxan-5-one 
• 188925-13-5 (2R,4S)-4-Benzyloxymethyl-2-methyl-[1,3]dioxan-5-one 
• 188925-43-1 (2R,4R,5R)-4-Benzyloxymethyl-5-ethyl-2-methyl-[1,3]dioxan-5-ol 

Relevant academic research and scientific papers

Synthesis and biological activity of 4-methyl-3,5-dioxane derivatives as thromboxane A2 receptor antagonists

The synthesis and biological activity of novel 4-methyl-3,5-dioxane analogues are described. All compounds were produced through modification of the substituent formally corresponding to the ω-octenol side chain of thromboxane A2 (TXA2/su

A new route for preparation of 2-deoxy-D-ribofuranose phospho sugar

The addition reaction of dimethyl phosphonate to (2R,4S)-4-(tert-butyldimethylsilyl)oxymethyl-2-methyl-1,3-dioxan-5-one (11a), followed by dehydroxylation, provided 1-O-(tert-butyldimethylsilyl)-3-deoxy-3-dimethoxy-phosphinoyl-2,4-O-ethylidene-d-erythritol (13a). Elongation of carbon skeleton of the d-erythrose (14) derived from 13a and then acidic methanolysis gave a mixture of methyl 2,4-dideoxy-4-dimethoxyphosphinoyl-α,β-d-erythro-pentopyranosides (7), which was led to 2-deoxy-D-ribofuranose phospho sugar (4) in an appreciably improved total yield compared with the procedures via previously reported route.