70385-91-0

Basic information

• Product Name: 7-amino-5H-pyrrolo[3,4-b]pyrazin-5-one
• CAS NO: 70385-91-0
• Molecular Formula: C₆H₄N₄O
• Molecular Weight: 148.1222
• Mol File: 70385-91-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 407.6°C at 760 mmHg
• Flash Point: 200.3°C
• Density: 1.84g/cm³
• Vapor Pressure: 7.48E-07mmHg at 25°C
• Refractive Index: 1.89
• CAS DataBase Reference: 7-amino-5H-pyrrolo[3,4-b]pyrazin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-amino-5H-pyrrolo[3,4-b]pyrazin-5-one(70385-91-0)
• EPA Substance Registry System: 7-amino-5H-pyrrolo[3,4-b]pyrazin-5-one(70385-91-0)

Safety Data

• Hazardous Substances Data: 70385-91-0(Hazardous Substances Data)

Upstream product

• 66505-29-1 3-cyanopyrazine-2-carboxamide 
• 13481-25-9 pyrazine-2,3-dicarbonitrile 

Relevant articles and documents

Cyclic acyl amidines as unexpected C4-donors for fully substituted pyridine ring formation in the base mediated reaction with malononitrile

A new one-step, pseudo four-component approach for the synthesis of fully substituted pyridines via ring-opening of the cyclic acyl amidine of 3-amino-1H-isoindol-1-one and its aza-analogues during the reaction with malononitrile in the presence of sodium methoxide, followed by pyridine ring closure is reported. This method allows the one-step preparation of previously unknown 2-(pyridin-4-yl)(hetero)aryl carboxamides in good yields under mild reaction conditions.