70415-59-7 Usage
Uses
Used in Research and Development:
N-nitrosomethyl-(3-hydroxypropyl)amine is used as a research compound for studying the properties and effects of MNPA and other related nitrosamines. Its role as an intermediate in the synthesis of MNPA makes it valuable for understanding the mechanisms of carcinogenesis and cytotoxicity associated with these compounds.
Used in Toxicology Studies:
Due to its higher cytotoxicity compared to other nitrosamines, N-nitrosomethyl-(3-hydroxypropyl)amine is utilized in toxicology studies to investigate the potential health risks and effects of exposure to MNPA and similar compounds. This helps in developing strategies for risk assessment, prevention, and mitigation of the harmful effects of these carcinogens.
Used in Regulatory Compliance and Monitoring:
N-nitrosomethyl-(3-hydroxypropyl)amine is also used in regulatory compliance and monitoring efforts to ensure the safety of consumer products and environmental conditions. By understanding the presence and effects of MNPA and related compounds, regulatory agencies can establish guidelines and standards to protect public health.
Safety Profile
Questionable carcinogen withexperimental carcinogenic data. When heated todecomposition it emits toxic vapors of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 70415-59-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,1 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 70415-59:
(7*7)+(6*0)+(5*4)+(4*1)+(3*5)+(2*5)+(1*9)=107
107 % 10 = 7
So 70415-59-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H10N2O2/c1-6(5-8)3-2-4-7/h7H,2-4H2,1H3
70415-59-7Relevant academic research and scientific papers
New Simple Polymeric Supports with Hydrazone Linkers for Solid-Phase Synthesis of Ketones and Primary Amines
Lazny, Ryszard,Nodzewska, Aneta,Wolosewicz, Karol
, p. 2858 - 2864 (2007/10/03)
The preparation of new solid supports with hydrazine anchoring groups and their application to solid-phase synthesis of ketones and primary amines are described. The supports were used for immobilization of ketones, 4-tert-butylcyclohexanone, pentan-3-one, acetone, N-methylpiperidone, N-benzylpiperidone, and tropinone in the form of their hydrazones. The polymer-supported hydrazones were subjected to deprotonation/alkylation procedure (LDA/RX) once or twice. The resulting alkylated products were cleaved off the solid support on treatment with trifluoroacetic acid in tetrahydrofuran providing α-alkylated or α,α′-bisalkylated ketones or were subjected to reductive cleavage with borane in tetrahydrofuran to give β-alkylated or β,β′-bisalkylated primary amines.
