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(3R,4aR,5R,6R)-6-hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one is a complex organic compound with a molecular formula of C15H22O2. It is a derivative of naphthalene and contains a hydroxyl group and a propenyl group. This hexahydronaphthalen-2(3H)-one is a cyclic ketone with a six-membered ring. As a chiral compound, it has multiple stereocenters, denoted by the (3R,4aR,5R,6R) in its name. The presence of functional groups such as the hydroxyl and propenyl groups make it potentially useful in organic synthesis and in pharmaceutical research.

70424-08-7

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70424-08-7 Usage

Uses

Used in Organic Synthesis:
(3R,4aR,5R,6R)-6-hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one is used as a key intermediate in organic synthesis for the production of various complex organic molecules. Its unique structure and functional groups allow for versatile chemical reactions, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3R,4aR,5R,6R)-6-hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one is used as a starting material for the development of new drugs. Its chiral centers and functional groups can be exploited to create enantiomerically pure compounds with potential therapeutic applications. Researchers can modify its structure to explore its biological activity and optimize its pharmacological properties for specific drug targets.
Used in Chiral Compounds Development:
(3R,4aR,5R,6R)-6-hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one is used as a precursor in the development of chiral compounds. Its multiple stereocenters make it an ideal candidate for studying the effects of stereochemistry on the properties and reactivity of molecules. This can lead to the discovery of novel chiral compounds with unique applications in various fields, such as asymmetric catalysis and enantioselective synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 70424-08-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,2 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 70424-08:
(7*7)+(6*0)+(5*4)+(4*2)+(3*4)+(2*0)+(1*8)=97
97 % 10 = 7
So 70424-08-7 is a valid CAS Registry Number.

70424-08-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R,4aR,5R,6R)-6-hydroxy-4a,5-dimethyl-3-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one

1.2 Other means of identification

Product number -
Other names 2(3H)-Naphthalenone,4,4a,5,6,7,8-hexahydro-6-hydroxy-4a,5-dimethyl-3-(1-methylethenyl)-,(3R,4aR,5R,6R)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70424-08-7 SDS

70424-08-7Upstream product

70424-08-7Downstream Products

70424-08-7Relevant academic research and scientific papers

Bioactive sesquiterpene derivatives from mangrove endophytic fungus Phomopsis sp. SYSU-QYP-23: Structures and nitric oxide inhibitory activities

Chen, Yan,Liu, Hongju,Zou, Ge,Yang, Wencong,Zhang, Lishan,Yan, Zhangyuan,Long, Yuhua,She, Zhigang

, (2020/12/21)

Eight new sesquiterpene derivatives (2, 4–6 and 10–13), along with five known analogues were isolated from the mangrove endophytic fungus Phomopsis sp. SYSU-QYP-23. Their structures of new compounds were established by spectroscopic methods, and the absol

Homopetasinic acid isolated from Diaporthe sp. strain 1308-05

Ito, Atsushi,Kumagai, Ikuya,Maruyama, Miku,Maeda, Hayato,Tonouchi, Akio,Nehira, Tatsuo,Kimura, Ken-Ichi,Hashimoto, Masaru

supporting information, p. 1117 - 1119 (2016/03/09)

Homopetasinic acid (1) was isolated from fungi of the Diaporthe sp. strain 1308-05. NMR spectroscopic structural analysis revealed a petasol (3) substructure and a (4E,6E)-7-carboxy-3-hydroxy-2-methylhepta-4,6-dienoate side chain. The absolute configuration of the petasol moiety was established by the specific rotation value after basic hydrolysis. The (2′S,3′S)-configuration of the side chain was determined by NMR empirical methods as well as comparison of the spectral data with related model compounds. The absolute structure of the side chain moiety was established on the basis of ECD spectral analyses involving theoretical calculations. The biological activities of 1 are also discussed.

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