70446-75-2

Basic information

• Product Name: diethyl (2,3,4,5-tetrafluoro-6-nitrophenyl)phosphonate
• CAS NO: 70446-75-2
• Molecular Weight: 331.16
• Mol File: 70446-75-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: diethyl (2,3,4,5-tetrafluoro-6-nitrophenyl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (2,3,4,5-tetrafluoro-6-nitrophenyl)phosphonate(70446-75-2)
• EPA Substance Registry System: diethyl (2,3,4,5-tetrafluoro-6-nitrophenyl)phosphonate(70446-75-2)

Safety Data

• Hazardous Substances Data: 70446-75-2(Hazardous Substances Data)

Upstream product

• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 880-78-4 pentafluoronitrobenzen 
• 120341-31-3 tert-butyldimethylsilyloxydiethyl phosphonic ester 
• 2303-76-6 sodium diethyl phosphite 
• 122-52-1 triethyl phosphite 

Relevant articles and documents

Organocatalytic Arylation of α-Ketoesters Based on Umpolung Strategy: Phosphazene-Catalyzed SNAr Reaction Utilizing [1,2]-Phospha-Brook Rearrangement

An organocatalytic arylation of α-ketoesters was developed on the basis of umpolung strategy. Phosphazene P2-tBu efficiently catalyzes the three-component coupling reaction of α-ketoesters, a silylated secondary phosphite, and electron-deficient fluoroarenes to provide α-hydroxyester derivatives possessing an electron-deficient aryl group at the α-position. The reaction involves the catalytic generation of α-oxygenated ester enolates from α-ketoesters through the [1,2]-phospha-Brook rearrangement followed by the SNAr reaction.