70449-93-3 Usage
Chemical class
Dibenzo cycloheptadiene derivatives
Relationship to clozapine
Major active metabolite of clozapine, an atypical antipsychotic medication
Therapeutic potential
Studied for its effects on schizophrenia and other psychiatric disorders
Mechanism of action
Potent antagonist of serotonin and dopamine receptors in the brain, leading to antipsychotic properties
Additional effects
Research suggests anti-inflammatory and neuroprotective properties
Pharmacological development
Promising target for further development due to its potential therapeutic effects and additional properties
Chemical structure
Contains a dihydro-12-hydroxy-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine core with a 10,11-dihydro and a 12-hydroxy group
Molecular weight
Approximately 279.35 g/mol (calculated from the molecular formula)
Check Digit Verification of cas no
The CAS Registry Mumber 70449-93-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,4 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 70449-93:
(7*7)+(6*0)+(5*4)+(4*4)+(3*9)+(2*9)+(1*3)=133
133 % 10 = 3
So 70449-93-3 is a valid CAS Registry Number.
70449-93-3Relevant academic research and scientific papers
5-Alkyl or hydroxyalkyl substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines and anticonvulsant use thereof
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, (2008/06/13)
5-Substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines, derivatives and pharmaceutically acceptable salts thereof are useful as anticonvulsants.
