704870-71-3Relevant academic research and scientific papers
ADENOSINE A3 RECEPTOR MODULATORS
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, (2019/12/30)
Modulators of the adenosine A3 receptors of formula (I): and process for preparing said compounds. Other aspects of the present invention are pharmaceutical compositions comprising an effective amount of said compounds and the use of said compo
TBHP/AIBN-Mediated Synthesis of 2-Amino-thioazoles from Active Methylene Ketones and Thiourea under Metal-free Conditions
Sun, Jiyun,Ge, Huaibin,Zhen, Xiaohua,An, Xuechan,Zhang, Guangtao,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang
, p. 2107 - 2114 (2018/03/26)
A new oxidative system of tert-butyl hydroperoxide (TBHP)/azodiisobutyronitrile (AIBN) has been used for the first time for a convenient, metal-free synthesis of substituted 2-aminothioazoles from active methylene ketone derivatives and thiourea. The reaction is postulated to proceed via an oxidative cyclization initiated by a radical process and followed by a condensation reaction.
Method for synthesizing 2-aminothiazole derivative
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Paragraph 0033; 0034; 0035, (2018/04/03)
The invention discloses a method for synthesizing a 2-aminothiazole derivative. The method comprises the following steps: by taking a ketone derivative (I) with an electron withdrawing group at the alpha position and thiourea (II) as raw materials, t-buty
THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS
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Paragraph 0132; 0133; 0136, (2017/12/27)
Modulators of adenosin A3 receptors of formula (I) and procedure for preparing these compounds. Other objectives of the present invention are to provide pharmaceutical compositions comprising an effective amount of these compounds and the use o
NEW COMPOUNDS AS ADENOSINE A1 RECEPTOR ANTAGONISTS
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Page/Page column 18-19, (2009/05/29)
This compounds correspond to the formula (I), where: R1 represents and aryl or heteroaryl group optionally substituted by one or more substituents selected from the group consisting of halogen atoms, straight or branched optionally substituted
2-ACYLAMINOTHIAZOLE DERIVATIVES
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Page/Page column 31, (2008/06/13)
The Invention relates to compounds of the formula I, wherein the variables are as defined in the claims, for use as a medicament. The compounds are A2A-receptor legends and are useful in the treatment of neurological and psychiatric disorders where an A2A-receptor is implicated.
