704890-29-9

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 704890-28-8 (4-hydroxy-3-methoxy-5-oxo-5H-furan-2-ylidene)-phenyl-acetic acid methyl ester 
• 101-41-7 benzeneacetic acid methyl ester 
• 704890-25-5 4-methoxy-3-oxo-2-phenyl-butyric acid methyl ester 
• 704890-26-6 (Z)-4-Methoxy-2-phenyl-3-trimethylsilanyloxy-but-2-enoic acid methyl ester 
• 704890-27-7 {(E)-3-Methoxy-1-[1-methoxy-1-trimethylsilanyloxy-meth-(Z)-ylidene]-2-trimethylsilanyloxy-allyl}-benzene 

Downstream Products

• 481-64-1 (E)-4-hydroxy-5-(α-methoxycarbonylbenzylidene)-3-(4-methoxyphenyl)furan-2(5H)-one 
• 22736-30-7 (E)-4-methoxy-5-(α-methoxycarbonylbenzylidene)-3-(4-methoxyphenyl)furan-2(5H)-one 
• 22628-22-4 (E)-4-methoxy-5-(α-methoxycarbonylbenzylidene)-3-phenylfuran-2(5H)-one 

Relevant academic research and scientific papers

Defunctionalization of γ-alkylidene-α-hydroxybutenolides by palladium(0)-catalyzed reaction of enol triflates with hexylboronic acid

The Suzuki reaction of hexylboronic acid with enol triflates derived from γ-alkylidene-α-hydroxybutenolides resulted in reductive formation of α-unsubstituted γ-alkylidenebutenolides. The formation of the products can be explained based on an "oxidative a

Suzuki cross-coupling reactions of γ-alkylidenebutenolides: Application to the synthesis of vulpinic acid

α-Hydroxy-γ-alkylidenebutenolides were efficiently functionalized by Suzuki cross-coupling reactions via the corresponding enol triflates. The natural product vulpinic acid was prepared by this methodology.