704892-97-7Relevant academic research and scientific papers
Synthesis of novel di- and trisaccharide mimetics with non-glycosidic amino bridges
Neumann, Janna,Weingarten, Saskia,Thiem, Joachim
, p. 1130 - 1144 (2008/02/06)
Synthesis of novel di- and trisaccharides using enzymatic glycosylation, Dess-Martin oxidation and reductive animation allows rapid access to the target structures. Thus, a novel class of glycomimetics was obtained having nitrogen inserted as bridging ato
A strategy for functional proteomic analysis of glycosidase activity from cell lysates
Vocadlo, David J.,Bertozzi, Carolyn R.
, p. 5338 - 5342 (2007/10/03)
A multipurpose flag: The inactivator 1 covalently labels the catalytic nucleophiles of retaining β-glycosidases to form species 2. The small azide group allows labeling of enzymes with sterically congested active sites. Staudinger ligation of 2 with phosp
Formation of LacNAc mimetics employing novel donor substrates for enzymatic β1→4 galactosylation
Weingarten, Saskia,Thiem, Joachim
, p. 961 - 962 (2007/10/03)
The formation of LacNAc mimetics employing novel donor substrates for enzymatic β1→4 galactosylation is discussed. In examining C-6 modified 4-nitrophenyl β-D-galacto-pyranosides as donor structures the β-galactosidase revealed a broad substrate specifici
