704906-80-9

Upstream product

• 704906-60-5 3-benzyloxy-4-[2-(tert-butyl-dimethyl-silanyloxy)-4-trimethylsilanyl-but-3-ynyl]-5-nitro-benzoic acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 187682-19-5 3-benzoyloxy-4-methyl-5-nitrobenzoic acid methyl ester 
• 1066-54-2 trimethylsilylacetylene 
• 704906-38-7 3-Benzyloxy-4-((R)-2-hydroxy-4-trimethylsilanyl-but-3-ynyl)-5-nitro-benzoic acid methyl ester 
• 704906-34-3 3-benzoyloxy-5-nitro-4-(2-oxoethyl)benzoic acid methyl ester 

Downstream Products

• 704906-84-3 {3-benzyloxy-4-[2-(tert-butyl-dimethyl-silanyloxy)-but-3-ynyl]-5-nitro-phenyl}-methanol 
• 704906-88-7 [1-(2-benzyloxy-4-benzyloxymethyl-6-nitro-benzyl)-prop-2-ynyloxy]-tert-butyl-dimethyl-silane 
• 704906-95-6 [(Z)-(R)-1-(2-Benzyloxy-4-benzyloxymethyl-6-nitro-benzyl)-3-iodo-allyloxy]-tert-butyl-dimethyl-silane 
• 704907-02-8 N-{3-benzyloxy-5-benzyloxymethyl-2-[2-(tert-butyl-dimethyl-silanyloxy)-4-iodo-but-3-enyl]-phenyl}-hydroxylamine 
• 704906-91-2 [1-(2-benzyloxy-4-benzyloxymethyl-6-nitro-benzyl)-3-iodo-prop-2-ynyloxy]-tert-butyl-dimethyl-silane 
• 704906-64-9 C₄₇H₅₈INO₄Si₂ 
• 704906-68-3 C₄₈H₅₇NO₅Si₂ 

Relevant academic research and scientific papers

Development of a flexible strategy towards FR900482 and the mitomycins

FR900482 and the mitomycins are two intriguing classes of alkaloid natural products that have analogous biological mechanisms and obvious structural similarity. Both classes possess potent anticancer activity, a feature that has led to their investigation

Pd-catalyzed carbonylative lactamization: A novel synthetic approach to FR900482

Matrix presented. An asymmetric synthesis of the benzazocine core of FR900482 has been achieved in 15 steps from 3,5-dinitro-p-toluic acid. Key features of the synthesis include an enantioselective N-methylephedrine-mediated zinc acetylide addition to a h