705290-37-5

Upstream product

• 141775-72-6 6-[3-chloro-4-(3-hydroxy-propoxy)-phenyl]-4,5-dihydro-2H-pyridazin-3-one 
• 3233-32-7 hydroquinone monoacetate 

Downstream Products

• 705290-38-6 6-{3-chloro-4-[3-(4-hydroxy-phenoxy)-propoxy]-phenyl}-4,5-dihydro-2H-pyridazin-3-one 

Relevant academic research and scientific papers

COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE

This invention provides compounds that possess inhibitory activity against β--adrenergic receptors and phosphodiesterase PDE, including phosphodiesterase 3 (PDE3 ). This invention further provides pharmaceutical compositions comprising such -compounds; methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine; and methods of preparing pharmaceutical compositions and compounds that possess inhibitory activity against ?-adrenergic receptors and PDE.