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EGS Crosslinker is a cleavable crosslinker that can be cleaved using hydroxylamine. It contains two NHS ester groups that can react with primary amines, making it a versatile reagent for various applications.

70539-42-3

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70539-42-3 Usage

Uses

Used in Biochemistry and Molecular Biology:
EGS Crosslinker is used as a cross-linking agent for connecting molecules through primary amines. This is particularly useful in the study of protein-protein interactions, enzyme activity, and other biochemical processes.
Used in Chemical Synthesis:
EGS Crosslinker is used as a bromoacetate amine and sulfhydryl reactive homobifunctional cross-linking reagent. This allows for the formation of covalent bonds between molecules, facilitating the synthesis of new compounds and materials.
Used in Research and Development:
EGS Crosslinker is used as a research tool to investigate the structure and function of biological molecules. Its cleavability and reactivity with primary amines make it a valuable asset in the development of new drugs, diagnostics, and therapeutics.

Biochem/physiol Actions

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent. It is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). The linkage provides a 12-atom spacer.

Check Digit Verification of cas no

The CAS Registry Mumber 70539-42-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,3 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 70539-42:
(7*7)+(6*0)+(5*5)+(4*3)+(3*9)+(2*4)+(1*2)=123
123 % 10 = 3
So 70539-42-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H20N2O12/c21-11-1-2-12(22)19(11)31-17(27)7-5-15(25)29-9-10-30-16(26)6-8-18(28)32-20-13(23)3-4-14(20)24/h1-10H2

70539-42-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-O-(2,5-dioxopyrrolidin-1-yl) 1-O-[2-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]oxyethyl] butanedioate

1.2 Other means of identification

Product number -
Other names EGS

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70539-42-3 SDS

70539-42-3Upstream product

70539-42-3Downstream Products

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