70553-45-6 Usage
Uses
NS 3763 is a selective non-competitive kainate receptor antagonist.
Biological Activity
Selective non-competitive kainate receptor antagonist; displays selectivity for GLU K5 subunit-containing receptors (IC 50 values are 1.6 and > 30 mM for homomeric GLU K5 and GLU K6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC 50 >> 30 mM).
Check Digit Verification of cas no
The CAS Registry Mumber 70553-45-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,5 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70553-45:
(7*7)+(6*0)+(5*5)+(4*5)+(3*3)+(2*4)+(1*5)=116
116 % 10 = 6
So 70553-45-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
