70580-80-2

Upstream product

• 72504-04-2 (+)-(1R)-(1α,2β,3β,4α,6β)-6-(acetylamino)-3-(acetylmethylamino)-4-O-methyl-1,2,4-cyclohexanetriol 
• 55990-89-1 (1α,2α,3β,4α,5α)-1,2:4,5-dianhydro-1,2,3,4,5-cyclohexane-pentol 
• 87782-22-7 (3aS,4R,5R,5aS,8aR,8bR)-4-Bromo-3-tert-butyl-5-methoxy-6-methyl-octahydro-benzo[1,2-d;4,3-d']bisoxazole-2,7-dione 
• 2699-13-0 3-methoxycyclohexene 
• 87782-14-7 (3aS,4R,7S,7aS)-7-Hydroxy-4-methoxy-3-methyl-3a,4,7,7a-tetrahydro-3H-benzooxazol-2-one 
• 53119-32-7 (2,3-dibromo-cyclohexyl)-methyl ether 
• 121916-68-5 (+)-(1S)-(1α,2β,3β,4α,6α)-6-ammonio-4-O-methyl-3-(methylammonio)-1,2,4-cyclohexanetriol sulfate 
• 1165952-91-9 cyclohexa-1,3-diene 
• 87902-31-6 DL-(1α,2β,3β,4α,6β)-6-azido-2-O,3-N-carbonyl-4-O-methyl-3-(methylamino)-1,2,4-cyclohexanetriol 
• 87902-30-5 DL-(1α,2α,3β,4β,5α)-1,2-anhydro-3-O,4-N-carbonyl-5-O-methyl-4-(methylamino)-1,2,3,5-cyclohexanetetrol 
• 6705-51-7 1,3-cyclohexadiene monoepoxide 
• 87902-29-2 (3aS,4R,7S,7aS)-7-Bromo-4-methoxy-3-methyl-hexahydro-benzooxazol-2-one 
• 87902-28-1 ((1R,6R)-6-Methoxy-cyclohex-2-enyl)-methyl-carbamic acid methyl ester 
• 87902-27-0 (1R,2R)-2-Methylamino-cyclohex-3-enol 

Downstream Products

• 94605-75-1 N-((1S,2R,3R,4S,5S)-2,3-Dihydroxy-5-methoxy-4-methylamino-cyclohexyl)-acetamide 
• 94605-75-1 N-((1R,2S,3S,4R,5R)-2,3-Dihydroxy-5-methoxy-4-methylamino-cyclohexyl)-acetamide 

Relevant academic research and scientific papers

Aminoglycoside Antibiotics - Enantiomerically Pure Sporamine Building Blocks

Starting from the 1,2:4,5-dianhydro-epi-deoxyinositol 2a (available ultimately from benzene) an expedient total synthesis of rac-sporamine (rac-3) has been developed.Key steps are two regiospecific and quantitative epoxide openings, effected intramolecula

Total Synthesis of (+/-)-Fortamine and (+/-)-2-Deoxyfortamine

The efficient conversion of 1,3-cyclohexadiene (7) to the aminocyclitols (+/-)-fortamine (4, 13 steps, 30percent overall yield) and (+/-)-2-deoxyfortamine (5, 10 steps, 54percent overall yield) features four regiospecific epoxide-opening reactions.

ISOLATION AND STRUCTURES OF ISTAMYCIN COMPONENTS

In addition to istamycin A and B previously isolated from culture filtrates of Streptomyces tenjimariensis, istomycin C, A0, B0, C0, A1, B1, C1, and A2 which contain the 1,4-diam