705977-01-1Relevant academic research and scientific papers
Synthesis and structure-activity relationship of 3-arylbenzoxazines as selective estrogen receptor β agonists
Yang, Wu,Wang, Yufeng,Ma, Zhengping,Golla, Rajasree,Stouch, Terry,Seethala, Ramakrishna,Johnson, Susan,Zhou, Rong,Guengoer, Timur,Feyen, Jean H.M.,Dickson Jr., John K.
, p. 2327 - 2330 (2007/10/03)
A series of 3-aryl-7-hydroxybenzoxazine analogues have been prepared and evaluated as ligands for the two estrogen receptor subtypes (ERα and ERβ). From the radioligand binding assay, compounds with more than a 10-fold binding selectivity toward the ERβ s
