70599-64-3Relevant academic research and scientific papers
Transition metal free large-scale synthesis of aromatic vinyl chlorides from aromatic vinyl carboxylic acids using bleach
Hatvate, Navnath T.,Takale, Balaram S.,Ghodse, Shrikant M.,Telvekar, Vikas N.
supporting information, p. 3892 - 3894 (2018/10/02)
While continuing our research on Hunsdiecker reaction, we came across an interesting application of bleach, sodium hypochlorite (NaOCl) for decarboxylative chlorination reaction. The reaction is easily scaled up to 10 mmol. The reaction has good tolerance towards wide variety of functional groups. The reaction has mild conditions and gave relatively high chemical yield of the desired product.
2-(2-Haloalkenyl)-aryl halides as substrates for palladium-catalysed tandem C-N bond formation: Efficient synthesis of 1-substituted indoles
Willis, Michael C.,Brace, Gareth N.,Findlay, Thomas J. K.,Holmes, Ian P.
, p. 851 - 856 (2007/10/03)
2-(2-Haloalkenyl)-aryl halides, conveniently prepared in a single step from the corresponding o-halobenzaldehydes, are combined with amines under Pd catalysis to provide 1-substituted indoles. All combinations of Br and Cl leaving groups can be employed,
Microwave induced halodecarboxylation of α,β-unsaturated carboxylic acids
Katritzky, Alan R.,Majumder, Suman,Jain, Ritu
, p. 1073 - 1075 (2007/10/03)
Halodecarboxylations of α,β-unsaturated carboxylic acids 1a-g, 4 by N-cholorobenzotriazole under 5-10 minutes of microwave irradiation gave the corresponding β-arylvinyl halides 3a-g, 5 in yields of 70-90%.
INVESTIGATIONS ON REACTIONS OF CHLORINE DIOXIDE AND SODIUM CHLORITE WITH ORGANIC COMPOUNDS. PART XXXV. REACTIONS OF CHLORINE DIOXIDE WITH RING-SUBSTITUTED STYRENES
Kwiecien, Halina,Jalowiczor, Jozef
, p. 811 - 824 (2007/10/02)
Reactions of chlorine dioxide with ring substituted styrenes (1a-n) in carbon tetrachloride at 52-54 deg C were studied.The reaction products were isolated and characterised.It has been found that methyl-, chloro-, nitrostyrenes and 4-methoxystyrene are attacked by chlorine dioxide exclusively on the vinyl group, to yield the corresponding α-chloroacetophenones (2), diastereoisomers of β-chlorostyrene (6,7), oxidation products (8,9) and some polymers.Oxidation of its phenolic hydroxyl groups and vinyl polymerization took place in hydroxystyrenes.
