70618-03-0

Basic information

• Product Name: 1-pyridin-2-ylethanone N-(3-fluorophenyl)thiosemicarbazone
• CAS NO: 70618-03-0
• Molecular Formula: C₁₄H₁₃FN₄S
• Molecular Weight: 288.3432
• Mol File: 70618-03-0.mol

Chemical Properties

• Boiling Point: 412.4°C at 760 mmHg
• Flash Point: 203.2°C
• Density: 1.25g/cm³
• Vapor Pressure: 5.2E-07mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 1-pyridin-2-ylethanone N-(3-fluorophenyl)thiosemicarbazone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-pyridin-2-ylethanone N-(3-fluorophenyl)thiosemicarbazone(70618-03-0)
• EPA Substance Registry System: 1-pyridin-2-ylethanone N-(3-fluorophenyl)thiosemicarbazone(70618-03-0)

Safety Data

• Hazardous Substances Data: 70618-03-0(Hazardous Substances Data)

Usage

Molecular Structure

1-pyridin-2-ylethanone N-(3-fluorophenyl)thiosemicarbazone consists of a pyridine ring, a carbon chain, and a thiosemicarbazone molecule with a 3-fluorophenyl group.

Chemical Compound

It is a complex chemical compound with potential for biological activity.

Medicinal Chemistry Interest

The compound is of interest in the field of medicinal chemistry due to its potential for biological activity.

Drug Development

It has potential for use in the development of new drugs.

Unique Structure

The compound's unique structure and functional groups make it a promising candidate for further exploration.

Drug Discovery

1-pyridin-2-ylethanone N-(3-fluorophenyl)thiosemicarbazone is a promising candidate for drug discovery and development.

Upstream product

• 1122-62-9 2-acetylpyridine 
• 70619-48-6 4-(3-fluorophenyl)-3-thiosemicarbazide 

Relevant articles and documents

Heterocyclic and aromatic thiosemicarbazones useful in the treatment of filariasis

This invention is directed to heterocyclic and aromatic thiosemicarbazonesseful in the treatment of filariasis and in an animal, including humans.

2-acetylpyridine thiosemicarbazone compositions as anitviral agents

This invention relates to various compositions, comprising a 2-acetylprid thiosemicarbazone and a diol, which are useful in the treatment of viral infections.

Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia

This invention relates to novel transition metal complexes of 2-acetyl- and-propionylpyridine thiosemicarbazones, their selenium analogs. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures u

2-acetyl- and 2-propionylpyridine selenosemicarbazones

This invention relates to novel 2-acetyl- and 2-propionylpyridine selenosemicarbazones. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures used to prepare the selenosemicarbazones.

2-acetylpyridine thiosemicarbazones as antiviral agents

This invention relates to the use of various 2-acetylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom in the treatment of viral infections. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.

2-Acetyl-and 2-propionylpyridine thiosemicarbazones

This invention relates to various 2-acetyl- and 2-propionylpyridine thioscarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malari

2-Acetylpyridine thiosemicarbazones. 1. A new class of potential antimalarial agents

Based on the antimalarial properties observed for 2-acetylpyridine 4-phenyl-3-thiosemicarbazone (1), an extensive series of related thiosemicarbazones was prepared and tested against Plasmodium berghei in mice. Screening results indicated that the presence of the 2-pyridylethylidene group was critical and that certain phenyl, benzyl, phenethyl, or cycloalkyl groups at N4 of the thiosemicarbazone moiety also contribute to antimalarial activity.