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7062-64-8

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7062-64-8 Usage

Molecular structure

2-[2-(2-methyl-3-phenylprop-2-en-1-ylidene)hydrazino]-5-(2-oxo-2-phenylethyl)-1,3-thiazol-4(5H)-one is a complex organic compound with a thiazole ring as its core structure.

Functional groups

The compound contains a hydrazine group (-NH-NH2), a phenyl group (-C6H5), and a ketone group (>C=O), which contribute to its potential reactivity and applications in various chemical and biological processes.

Aromaticity

The presence of the phenyl group indicates that the compound has aromatic properties, which can influence its stability and reactivity in chemical reactions.

Stereochemistry

The compound has a chiral center at the 2-position of the thiazole ring, which means it can exist as enantiomers or diastereomers. This can affect its biological activity and potential pharmaceutical applications.

Potential applications

Due to its complex structure and diverse functional groups, the compound may have potential applications in pharmaceuticals, organic synthesis, and other areas of chemistry and biology.

Further investigation

The intricate structure of the compound suggests that it may be a promising candidate for further research, including studies on its synthesis, reactivity, and potential applications in various chemical and biological processes.

Check Digit Verification of cas no

The CAS Registry Mumber 7062-64-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,6 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7062-64:
(6*7)+(5*0)+(4*6)+(3*2)+(2*6)+(1*4)=88
88 % 10 = 8
So 7062-64-8 is a valid CAS Registry Number.

7062-64-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-(2-methyl-3-phenylprop-2-enylidene)hydrazinyl]-5-phenacyl-1,3-thiazol-4-one

1.2 Other means of identification

Product number -
Other names (4-t-butylphenyl)(oxo)acetaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7062-64-8 SDS

7062-64-8Relevant articles and documents

Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors

Ahmed, S. Kaleem,Haese, Nicole N.,Cowan, Jaden T.,Pathak, Vibha,Moukha-Chafiq, Omar,Smith, Valerie J.,Rodzinak, Kevin J.,Ahmad, Fahim,Zhang, Sixue,Bonin, Kiley M.,Streblow, Aaron D.,Streblow, Cassilyn E.,Kreklywich, Craig N.,Morrison, Clayton,Sarkar, Sanjay,Moorman, Nathaniel,Sander, Wes,Allen, Robbie,Defilippis, Victor,Tekwani, Babu L.,Wu, Mousheng,Hirsch, Alec J.,Smith, Jessica L.,Tower, Nichole A.,Rasmussen, Lynn,Bostwick, Robert,Maddry, Joseph A.,Ananthan, Subramaniam,Gerdes, John M,Augelli-Szafran, Corinne E.,Suto, Mark J.,Morrison, Thomas E.,Heise, Mark T.,Streblow, Daniel N.,Pathak, Ashish K.

, p. 4762 - 4786 (2021)

A benzo[6]annulene, 4-(tert-butyl)-N-(3-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl) benzamide (1a), was identified as an inhibitor against Chikungunya virus (CHIKV) with antiviral activity EC90 = 1.45 μM and viral titer reduction (VTR) of 2.5 log at 10 μM

Nature of the Nucleophilic Oxygenation Reagent Is Key to Acid-Free Gold-Catalyzed Conversion of Terminal and Internal Alkynes to 1,2-Dicarbonyls

Dubovtsev, Alexey Yu.,Shcherbakov, Nikolay V.,Dar'in, Dmitry V.,Kukushkin, Vadim Yu.

, p. 745 - 757 (2020/02/04)

2,3-Dichloropyridine N-oxide, a novel oxygen transfer reagent, allows the conductance of the gold(I)-catalyzed oxidation of alkynes to 1,2-dicarbonyls in the absence of any acid additives and under mild conditions to furnish the target species, including those derivatized by highly acid-sensitive groups. The developed strategy is effective for a wide range of alkyne substrates such as terminal- and internal alkynes, ynamides, alkynyl ethers/thioethers, and even unsubstituted acetylene (40 examples; yields up to 99%). The oxidation was successfully integrated into the trapping of reactive dicarbonyls by one-pot heterocyclization and into the synthesis of six-membered azaheterocycles. This synthetic acid-free route was also successfully applied for the total synthesis of a natural 1,2-diketone.

Iridium-Catalyzed Asymmetric Hydrogenation of Unsaturated Piperazin-2-ones

Wang, Yanzhao,Liu, Yuanyuan,Li, Kun,Yang, Guoqiang,Zhang, Wanbin

supporting information, p. 1933 - 1941 (2017/06/09)

Two different iridium catalyst systems, generated from the ruthenocene-based phosphine-oxazoline ligand tBu-mono-RuPHOX or the diphosphine ligand BINAP, were developed for the asymmetric hydrogenation of 5,6-dihydropyrazin-2(1H)-ones, affording chiral piperazin-2-ones in good yields and with moderate to good ees. Different catalytic behaviors for the hydrogenation of these types of substrate were observed with these two catalyst systems. Our tBu-mono-RuPHOX ligand, which bears a ruthenocene scaffold with planar chirality, was found to be the best ligand for the [Ir(L)(COD)]BArF catalyst system, affording the desired products with up to 94% ee. (Figure presented.).

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