7064-33-7 Usage
Uses
Used in Pharmaceutical Research:
5-(3-BROMOPHENYL)ISOXAZOLE is used as a research compound for its potential biological activities, including antimicrobial, antifungal, and anti-inflammatory properties. Its unique structure and functional groups make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry:
As a heterocyclic compound, 5-(3-BROMOPHENYL)ISOXAZOLE is used as a key intermediate in the synthesis of various pharmaceuticals and bioactive molecules. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the resulting compounds, enhancing their therapeutic efficacy.
Used in Organic Synthesis:
5-(3-BROMOPHENYL)ISOXAZOLE is used as a building block in the synthesis of other organic compounds for research and industrial purposes. Its versatile structure allows for further functionalization and modification, enabling the creation of novel compounds with potential applications in various fields.
Used in Chemical Libraries:
5-(3-BROMOPHENYL)ISOXAZOLE is used as a component of chemical libraries for high-throughput screening in drug discovery. Its inclusion in such libraries facilitates the identification of lead compounds with potential therapeutic applications.
Used in Material Science:
Although not explicitly mentioned in the provided materials, given the compound's unique structure and properties, 5-(3-BROMOPHENYL)ISOXAZOLE may also find applications in material science, such as in the development of new polymers, sensors, or other advanced materials with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 7064-33-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,6 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7064-33:
(6*7)+(5*0)+(4*6)+(3*4)+(2*3)+(1*3)=87
87 % 10 = 7
So 7064-33-7 is a valid CAS Registry Number.
InChI:InChI=1/C31H38N4O4S2/c1-7-11-34-28(33-17-19(2)13-20(3)18-33)23(21(4)24(16-32)29(34)36)15-27-30(37)35(31(40)41-27)12-10-22-8-9-25(38-5)26(14-22)39-6/h8-9,14-15,19-20H,7,10-13,17-18H2,1-6H3
7064-33-7Relevant academic research and scientific papers
Harnessing Stereospecific Z-Enamides through Silver-Free Cp?Rh(III) Catalysis by Using Isoxazoles as Masked Electrophiles
Debbarma, Suvankar,Bera, Sourav Sekhar,Maji, Modhu Sudan
, p. 835 - 839 (2019/01/26)
The stereospecific synthesis of Z-enamides is described in this paper. For the first time, isoxazoles have been employed as electrophiles in C-H functionalization to afford thermodynamically less stable Z-enamides utilizing salicylaldehydes in an atom- and step-economic fashion. The stereochemistry of enamides might originate from the relative disposition of atoms present in isoxazole and the intramolecular hydrogen bonding. The reaction showed excellent scope as several structurally and electronically diverse salicylaldehydes and isoxazoles reacted efficiently.
A novel synthesis of 5-substituted isoxazoles from propargylic amines and N-hydroxyphthalimide
Zhang, Yicheng,Chen, Wei,Jia, Xueshun
supporting information, p. 2181 - 2183 (2018/05/08)
A mild and efficient method for the synthesis of 5-substituted isoxazoles through cyclization of propargylic amines with N-hydroxyphthalimide (NHPI) under metal-free conditions was developed.
Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity
Qian, Yong,Schürmann, Marc,Janning, Petra,Hedberg, Christian,Waldmann, Herbert
, p. 7766 - 7771 (2016/07/07)
Woodward's reagent K (WRK) is a reactive heterocyclic compound that has been employed in protein chemistry to covalently and unspecifically label proteins at nucleophilic amino acids, notably at histidine and cysteine. We have developed a panel of WRK-der
