70659-95-9

Basic information

• Product Name: (4-fluorobutoxy)benzene
• Synonyms: (4-fluorobutoxy)benzene
• CAS NO: 70659-95-9
• Molecular Weight: 168.211
• Mol File: 70659-95-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4-fluorobutoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (4-fluorobutoxy)benzene(70659-95-9)
• EPA Substance Registry System: (4-fluorobutoxy)benzene(70659-95-9)

Safety Data

• Hazardous Substances Data: 70659-95-9(Hazardous Substances Data)

Upstream product

• 1927-71-5 4-phenoxybutan-1-ol 
• 373-52-4 bromofluoromethane 
• 588-63-6 3-phenoxypropyl bromide 
• 462-72-6 4-bromo-1-fluorobutane 
• 71-43-2 benzene 
• 1200-03-9 4-bromophenyl butyl ether 
• 1120341-41-4 PhO(CH₂)3CF(SO₂Ph)2 

Relevant articles and documents

Efficient SN2 fluorination of primary and secondary alkyl bromides by copper(I) fluoride complexes

Copper(I) fluoride complexes ligated by phenanthroline derivatives have been synthesized and structurally characterized by X-ray crystallography. These complexes adopt as either ionic or neutral forms in the solid state, depending on the steric bulkiness of the substituent groups on the phenanthroline ligands. These complexes react with primary and secondary alkyl bromides to produce the corresponding alkyl fluorides in modest to good yields. This new method is compatible with a variety of important functional groups such as ether, thioether, amide, nitrile, methoxyl, hydroxyl, ketone, ester, and heterocycle moieties.

Promising fungicides from allelochemicals: Synthesis of umbelliferone derivatives and their structure–activity relationships

Umbelliferone was discovered to be an important allelochemical in our previous study, but the contribution of its activity and structure has not yet been revealed. In this study, a series of analogues were synthesized to determine the skeleton of umbelliferone and examine its fungicidal activity. Furthermore, targeted modifications were conducted with three plant parasitic fungi to examine the lead compounds. Among those tested, compounds 2f and 10 were found to show excellent antifungal activity with an inhibitory rate over 80% at 100 ug/mL. The study proves that umbelliferone can be a promising skeleton for fungicides discovery. In addition, the primary structure–activity relationship provides a good guidance for the discovery of novel fungicides based on natural products in the future.

Efficient nucleophilic fluoromethylation and subsequent transformation of alkyl and benzyl halides using fluorobis(phenylsulfonyl)methane

An efficient methodology for the nucleophilic fluoromethylation of alkyl and benzyl halides using r-fluoro-α-(phenylsulfonyl)methane (1) as a highly versatile reagent is reported. Using benzyl halides, stereospecific one-pot synthesis of α-fluorovinyl com