7066-36-6Relevant academic research and scientific papers
Selective and efficient fluorination of chlorodiazines under solvent-free phase transfer catalysis
Marque, Sylvain,Snoussi, Hanane,Loupy, André,Plé, Nelly,Turck, Alain
, p. 1847 - 1851 (2007/10/03)
3-Chloro-6-phenylpyridazine, 2,3-dichloroquinoxaline and 1,4-dichlorophthalazine were reacted with KF under solvent-free conditions in the presence of a phase transfer agent, with or without microwave irradiation. The chlorine-fluorine exchanges were obta
Selective fluorination by halogen exchange of chlorodiazines and chloropyridines promoted by the 'proton sponge' - Triethylamine tris(hydrogen fluoride) system
Darabantu, Mircea,Lequeux, Thierry,Pommelet, Jean-Claude,Plé, Nelly,Turck, Alain
, p. 739 - 750 (2007/10/03)
The 'proton sponge' - triethylamine tris(hydrogen fluoride) mixtures provide a mild and efficient fluorinating reagent to introduce selectively fluorine atoms by halogen exchange into chlorodiazines and chloronitropyridine series.
The proton sponge-triethylamine tris(hydrogen fluoride) system as a selective nucleophilic fluorinating reagent for chlorodiazines
Darabantu, Mirce,Lequeux, Thierry,Pommelet, Jean-Claude,Plé, Nelly,Turck, Alain,Toupet, Lo?c
, p. 6763 - 6767 (2007/10/03)
The proton sponge-triethylamine tris(hydrogen fluoride) mixture provides a mild and efficient fluorinating - reagent for the selective introduction of a fluorine atom, by halogen exchange, into dichlorodiazines. (C) 2000 Elsevier Science Ltd.
Elemental fluorine. Part 10.1 Selective fluorination of pyridine, quinoline and quinoxaline derivatives with fluorine-iodine mixtures
Chambers, Richard D.,Parsons, Mandy,Sandford, Graham,Skinner, Christopher J.,Atherton, Malcolm J.,Moilliet, John S.
, p. 803 - 810 (2007/10/03)
Selective fluorination of a range of pyridine and quinoline substrates to give corresponding 2-fluoro-derivatives can be readily achieved in high yield at room temperature using elemental fluorine-iodine mixtures. Reaction of fluorine with iodine forms, in situ, systems that function like sources of both iodonium and fluoride ions and fluorination of heterocyclic derivatives is suggested to proceed by fluoride ion attack on intermediate W-iodo-heterocyclic species. Quinoxaline derivatives react under similar conditions to give either the 2-fluoro- or 2,3-difluoro-quinoxaline derivatives depending on the ratio of fluorine passed through the solution. In related processes, pyridine can be alkoxylated upon reaction of an appropriate alcohol and fluorine.
FACILE SYNTHESIS AND HERBICIDAL ACTIVITIES OF NOVEL FLUOROQUINOXALINES
Makino, Kenzi,Yoshioka, Hirosuke
, p. 1215 - 1220 (2007/10/02)
The synthesis of new 2-fluoro-, 3-fluoro- and 2,3-difluoroquinoxalines by nucleophilic substitution with cesium fluoride as coupled with 18-crown-6 and their herbicidal activities are described.
