70671-47-5

Usage

Uses

Used in Nutritional Supplements:
(2R,3S)-3-amino-2-hydroxybutanoic acid is used as a nutritional supplement to support the synthesis of proteins and maintain overall health, as it is an essential amino acid that must be obtained from the diet.
Used in Food Industry:
(2R,3S)-3-amino-2-hydroxybutanoic acid is used as a food additive to enhance the nutritional value of products, as it can be found in various foods such as meat, dairy products, and leafy green vegetables.
Used in Pharmaceutical Industry:
(2R,3S)-3-amino-2-hydroxybutanoic acid is used as a building block for the synthesis of other amino acids and important compounds in the body, making it a valuable component in the development of pharmaceutical products.

Upstream product

• 70686-89-4 (4S,5R)-4-Methyl-2-oxooxazolidin-5-carbonsaeure 
• 340179-50-2 (2R,3S)-3-(dibenzylamino)-2-hydroxybutanoic acid 
• 339161-04-5 (2R,3S)-isothreonine hydrochloride 

Downstream Products

• 70686-89-4 (4S,5R)-4-Methyl-2-oxooxazolidin-5-carbonsaeure 

Relevant academic research and scientific papers

Improved stereoselectivity in intramolecular SN2′ cyclization through use of mechanistic principles

Valine and alanine were converted into the corresponding α-hydroxy-β-amino acids through intramolecular SN2′ cyclization. The novel cyclization protocol relied upon the use of N-benzyl-protected carbamates derived from α-amino acids. Georg Thie

Synthesis of all four stereoisomers of 3-amino-2-hydroxybutanoic acids

All four stereoisomers of 3-amino-2-hydroxybutanoic acids were been obtained as single enantiomers via stereospecific reactions from D-gulonic acid γ-lactone and D-glucono-δ-lactone.

Stereocontrolled asymmetric synthesis of α-hydroxy-β-amino acids. A stereodivergent approach

The stereocontrolled asymmetric synthesis of α-hydroxy-β-amino acids has been investigated via the Lewis acid-promoted cyanation of (5R,6S)-2-acetoxy-4-(benzyloxycarbonyl)-5, 6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazines with trimethylsilyl cyanide. Base-

Stereoselective cyanation of chiral α-amino aldehydes by reaction with Nagata's reagent: A route to enantiopure β-amino-α-hydroxy acids

Chiral α-dibenzylamino aldehydes react with diethylaluminum cyanide leading to anti-β-dibenzylamino-α-hydroxycyanides as the major diastereoisomers in good yields and diastereomeric excesses. Hydrolysis of the nitrile derivatives allows the synthesis of enantiopure β-amino-α-hydroxy acids.

Synthesis of 'D-Isothreonine' and 'L-Alloisothreonine' Starting form L-Alanine

Starting from L-alanine, 'D-isothreonine' (=(2R,3S)-3-amino-2-hydroxybutanoic acid) and 'L-alloisothreonine' (=(2S,3S)-3-amino-2-hydroxybutanoic acid) were synthesized.