706806-64-6 Usage
General Description
BOC-(R)-ALPHA-(4-FLUOROBENZYL)-PROLINE is a chemical compound that comprises a proline amino acid with a fluorobenzyl group attached to it, and this compound is in a protected form by a BOC (tert-butyloxycarbonyl) group. The functionalities of this compound are multifaceted, as it is most commonly found in scientific research and in the pharmaceutical industry. Known for its properties as a building block in the synthesis of peptides, it is used in making drugs and biochemical studies. Its stereochemistry, comprised of the (R) enantiomer, is significant as it could provide specificity in chemical reactions and biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 706806-64-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,6,8,0 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 706806-64:
(8*7)+(7*0)+(6*6)+(5*8)+(4*0)+(3*6)+(2*6)+(1*4)=166
166 % 10 = 6
So 706806-64-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H22FNO4/c1-16(2,3)23-15(22)19-10-4-9-17(19,14(20)21)11-12-5-7-13(18)8-6-12/h5-8H,4,9-11H2,1-3H3,(H,20,21)/t17-/m1/s1
706806-64-6Relevant articles and documents
Interrupted Curtius Rearrangements of Quaternary Proline Derivatives: A Flow Route to Acyclic Ketones and Unsaturated Pyrrolidines
Baumann, Marcus,Moody, Thomas S.,Smyth, Megan,Wharry, Scott
, p. 14199 - 14206 (2021/07/20)
Conversion of N-Boc-protected quaternary proline derivatives under thermal Curtius rearrangement conditions was found to afford a series of ring-opened ketone and unsaturated pyrrolidine products instead of the expected carbamate species. The nature of the substituent on the quaternary carbon thereby governs the product outcome due to the stability of a postulated N-acyliminium species. A continuous flow process with in-line scavenging was furthermore developed to streamline this transformation and safely create products on a gram scale.
