70691-68-8Relevant academic research and scientific papers
Heterocyclic effect for optical properties of naphthoquinone-based pigment: 2-methyl-3-heteroarylthio-1,4-naphthalenedione
Sako, Akihiro,Okuda, Koji,Tajima, Nobuo,Kuroda, Reiko,Imai, Yoshitane
, p. 2068 - 2073 (2017)
Three novel naphthoquinone-based heterocyclic pigments, 2-methyl-3-[(1-methyl-1H-imidazol-2-yl)thio-1,4-naphthalenedione, (4-methyl-4H-1,2,4-triazol-3-yl)thio-1,4-naphthalenedione, and (1-methyl-1H-tetrazol-5-yl)thio]-1,4-naphthalenedione, are synthesized, and their optical properties in both solution and solid states are investigated. Depending on the heteroarylthio ring in the pigment, variation in optical properties is observed, e.g. characteristic colours for each pigment in the solution and solid states. The achiral pigment containing the 1-methyl-1H-tetrazol-5-yl ring exhibits a chiral space group and a CD signal in the solid state.
NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
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Page/Page column 87; 89; 100, (2015/11/27)
Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.
Silver-Catalyzed Direct Thiolation of Quinones by Activation of Aryl Disulfides to Synthesize Quinonyl Aryl Thioethers
Zhang, Cheng,McClure, Jesse,Chou, C. James
, p. 4919 - 4927 (2015/06/02)
A silver-catalyzed coupling reaction of quinones with aryl disulfides for the synthesis of quinonyl aryl thioethers is described. In the presence of AgOAc (0.2 equiv)/dppp (0.24 equiv) as the catalyst, (NH4)2S2O8/sub
Green synthesis of thiophenyl-1,4-naphthoquinones
Kanodia, Saraswati,Thapliyal, Prakash Chander
, p. 833 - 836 (2012/10/29)
Reaction of 1,4-naphthoquinones adsorbed on neutral alumina to thiophenols in ambient conditions gave respective mono thiophenyl 1,4-naphthoquinones regioselectively in quantitative yield. The solvent free synthesis and quantitative conversion makes the process practical method.
Synthesis and selective anticancer activity of organochalcogen based redox catalysts
Doering, Mandy,Ba, Lalla A.,Lilienthal, Nils,Nicco, Carole,Scherer, Christiane,Abbas, Muhammad,Zada, Abdul Ali Peer,Coriat, Romain,Burkholz, Torsten,Wessjohann, Ludger,Diederich, Marc,Batteux, Frederic,Herling, Marco,Jacob, Claus
supporting information; experimental part, p. 6954 - 6963 (2010/12/25)
Many tumor cells exhibit a disturbed intracellular redox state resulting in higher levels of reactive oxygen species (ROS). As these contribute to tumor initiation and sustenance, catalytic redox agents combining significant activity with substrate specif
Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents
Mecklenburg, Susanne,Shaaban, Saad,Ba, Lalla A.,Burkholz, Torsten,Schneider, Thomas,Diesel, Britta,Kiemer, Alexandra K.,Roeseler, Anne,Becker, Katja,Reichrath, Joerg,Stark, Alexandra,Tilgen, Wolfgang,Abbas, Muhammad,Wessjohann, Ludger A.,Sasse, Florenz,Jacob, Claus
body text, p. 4753 - 4762 (2009/12/08)
Various human illnesses, including several types of cancer and infectious diseases, are related to changes in the cellular redox homeostasis. During the last decade, several approaches have been explored which employ such disturbed redox balances for the
