70724-70-8

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-Methoxyethyl)piperidine is used as a building block for the synthesis of various therapeutic agents, particularly for the development of antidepressant and anti-inflammatory drugs. Its piperidine structure is a common feature in many medications, making it a valuable component in the creation of new pharmaceutical compounds.
Used in Organic Chemistry:
4-(2-Methoxyethyl)piperidine is used as a reagent in organic chemistry for the synthesis of more complex chemical compounds. Its unique structure and reactivity allow for the creation of a wide range of molecules, making it a versatile component in the field of organic synthesis.
Used in Drug Development:
4-(2-Methoxyethyl)piperidine is used as a key intermediate in the development of new drugs, particularly in the area of medicinal chemistry. Its presence in many existing therapeutic agents highlights its potential for further exploration and utilization in the creation of novel pharmaceuticals with improved efficacy and safety profiles.

InChI:InChI=1/C8H17NO/c1-10-7-4-8-2-5-9-6-3-8/h8-9H,2-7H2,1H3

Upstream product

• 141047-55-4 N-fromyl-4-(2-methoxyethyl)piperidine 
• 622-26-4 4-(2-Hydroxyethyl)piperidine 
• 141047-47-4 N-formyl-4-(2-hydroxyethyl)piperidine 
• 70289-28-0 4-(2-methoxyethyl)pyridine 
• 509147-79-9 tert-butyl 4-(2-methoxyethyl)piperidine-1-carboxylate 

Downstream Products

• 141047-63-4 4-(2-methoxyethyl)piperidine amide of L-phenyllactic acid 
• 141062-21-7 (S)-2-{(S)-1-Benzyl-2-[4-(2-methoxy-ethyl)-piperidin-1-yl]-2-oxo-ethoxy}-hexanoic acid ((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-amide 
• 141047-81-6 (S)-2-{(S)-1-Benzyl-2-[4-(2-methoxy-ethyl)-piperidin-1-yl]-2-oxo-ethoxy}-hexanoic acid 

Relevant academic research and scientific papers

PHARMACEUTICAL COMPOUNDS

Fused pyrimidines of formula (I); wherein A represents a thiophene or furan ring; n is 1 or 2; R1 is a group of formula (II); wherein m is 0 or 1; R30 is H or C1-C6 alkyl; R4 and R5 form, together with the N atom to which they are attached, a 5- or 6-membered saturated N-containing heterocyclic group which includes 0 or 1 additional heteroatoms selected from N, S and O, which may be fused to a benzene ring and which is unsubstituted or substituted; or one of R4 and R5 is alkyl and the other is a 5- or 6-membered saturated N-containing heterocyclic group as defined above or an alkyl group which is substituted by a 5- or 6-membered saturated N-containing heterocyclic group as defined above; R2 is selected from formula (a); wherein R6 and R7 form, together with the nitrogen atom to which they are attached, a morpholine, thiomorpholine, piperidine, piperazine, oxazepane or thiazepane group which is unsubstituted or substituted; and formula (b); wherein Y is a C2-C4 alkylene chain which contains, between constituent carbon atoms of the chain and/or at one or both ends of the chain, 1 or 2 heteroatoms selected from O, N and S, and which is unsubstituted or substituted; and R3 is an indazole group which is unsubstituted or substituted; and the pharmaceutically acceptable salt thereof have activity as inhibitors of P13K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with P13 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.

Benzimidazolidinone derivatives as muscarinic agents

Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the same, as well as methods of treating psychosis using these compounds are disclosed.

Nonpeptide Renin Inhibitors Employing a Novel 3-Aza(or oxa)-2,4-dialkyl Glutaric Acid Moiety as a P2/P3 Amide Bond Replacement

A new series of renin inhibitors has been developed.The inhibitors feature a novel replacement for the P2/P3 dipeptide moiety normally associated with renin inhibitors.The dipeptide replacement was a (2S,4S)-3-aza(or oxa)-2,4-dialkylglutaric acid amide.Ex

1-PIPERIDINOPHTHALAZINES AS CARDIAC STIMULANTS

A series of 1-piperidinophthalazine derivatives as phosphodiesterase inhibitors and cardiac stimulants