70748-49-1

Usage

Uses

Used in Organic Synthesis:
1a,2,3,6,7,9,10a,13,14,14a-Decahydro-1a,5,8,12-tetramethyloxireno[9,10]cyclotetradeca[1,2-b]furan is used as a building block for the synthesis of other complex organic compounds due to its unique structure and potential reactivity.
Used in Pharmaceutical Research:
1a,2,3,6,7,9,10a,13,14,14a-Decahydro-1a,5,8,12-tetramethyloxireno[9,10]cyclotetradeca[1,2-b]furan is used as a starting material for the development of new pharmaceutical agents due to its novel structure and potential biological activity.
Note: The specific uses and potential hazards of 1a,2,3,6,7,9,10a,13,14,14a-Decahydro-1a,5,8,12-tetramethyloxireno[9,10]cyclotetradeca[1,2-b]furan are not well-documented, and further research is needed to fully understand its properties and potential applications.

InChI:InChI=1/C20H30O2/c1-14-6-5-11-20(4)19(22-20)10-8-15(2)12-18-17(9-7-14)16(3)13-21-18/h6,12,18-19H,5,7-11,13H2,1-4H3/b14-6+,15-12+/t18-,19-,20-/m0/s1

Upstream product

• 1043616-74-5 C₂₀H₃₂O₃ 
• 1042909-28-3 C₂₀H₃₁ClO₂ 
• 1042909-29-4 C₂₀H₃₁ClO₂ 
• 70645-54-4 (-)-sarcophytonin A 

Downstream Products

• 55038-27-2 Sarcophine 
• 74740-97-9 (2E,11E)-(6S,8S)-3,8,12,16-Tetramethyl-7,18-dioxa-tricyclo[13.3.0.0^6,8]octadeca-1⁽¹⁵⁾,2,11,16-tetraene 
• 137762-26-6 (1E,11E)-(6S,8S)-3-Hydroxy-3,8,12,16-tetramethyl-7,18-dioxa-tricyclo[13.3.0.0^6,8]octadeca-1,11,15-trien-17-one 
• 137762-25-5 (1E,11E)-(6S,8S)-3-Hydroperoxy-3,8,12,16-tetramethyl-7,18-dioxa-tricyclo[13.3.0.0^6,8]octadeca-1,11,15-trien-17-one 

Relevant academic research and scientific papers

Acid-catalyzed reactions of sarcophytoxide, a marine cembranoid: An apparently enantio-directive reaction, unusual products and stereochemical reconsideration of epoxide-ketone rearrangement

Perchloric acid treatment of sarcophytoxide, a marine cembranoid possessing an epoxide, brought about epoxide ketone rearrangement affording ketones. When the reaction time was long (22 h), a minor ketone that was antipodal to the ketone obtained in a short-time (l0min) reaction was formed. These puzzling findings, considering that the starting epoxide had three asymmetric carbons, were interpreted by surveying the structures of other ketonic products. The stereochemistry of a major ketone, which had been wrongly assigned, was corrected by extensive analyses of NMR spectra. The correct stereochemistry indicated that the epoxide-ketone rearrangement took a course via a cationic intermediate.

STUDIES OF AUSTRALIAN SOFT CORALS. XLV. EPOXIDATION REACTIONS OF CEMBRANOID DITERPENES: STEREOCHEMICAL OUTCOMES

Epoxidation of the cembranoid diterpene (1) afforded the known 7S,8S-epoxide (2), the 7R,8R-epoxide (3), the 11R,12R-epoxide (4) and the 11S,12S-epoxide (5) in the ratio 1:3:3:10.Similar epoxidation of the cembranolide (1R,2R,3E,7E,11E)-cembra-3,7,11,15-tetren-17,2-olide(6) afforded the 7S,8S-epoxide (7), the 7R,8R-epoxide (8), the 11R,12R-epoxide (9) and the 11S,12S-epoxide (10) in the ratio of 1:5:6:8.Only one of the products (8), from the second epoxidation reaction was known.The other three compounds are reported for the first time.This study reveals a significant preference for epoxidation at the 11,12-double bond.No evidence of epoxidation at the 3,4-double bond was detected in either system.