70751-53-0Relevant articles and documents
Synthesis of L-Alanyl-3-O-(β-D-xylopyranosyl)-L-seryl-glycyl-L-isoleucine. Direct Glycosydation of Peptides
Paulsen, Hans,Brenken, Mathias
, p. 649 - 654 (2007/10/02)
Glycosidation of the tetrapeptide 8 either with 1,2,3,4-tetra-O-acetyl-β-D-xylopyranose (1) under catalysis of trimethylsilyl triflate or with ethyl 2,3,4-tri-O-benzoyl-1-thio-β-D-xylopyranoside (4) using DMTST as promotor, leads to the O-glycopeptides 10 and 9.Deblocking of 10 affords the glycopeptide L-Ala-3-O-(β-D-Xylp)-L-Ser-Gly-L-Ile (11), which represents the N-terminal amino acid sequence 3 to 6 of the protein core of a proteodermantan sulfate.