70783-75-4

Usage

Uses

Used in Pesticide and Herbicide Industry:
2-CHLORO-4-TRIFLUOROMETHOXYPHENOL is utilized as an active ingredient in pesticides and herbicides for its ability to control and eliminate a wide range of pests and unwanted plant species. Its effectiveness in this application is attributed to its chemical structure, which allows it to interfere with the growth and development of target organisms.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-CHLORO-4-TRIFLUOROMETHOXYPHENOL serves as a key intermediate in the synthesis of various organic compounds and drugs. Its unique chemical properties make it a valuable building block for the development of new medications with diverse therapeutic applications.
Used in Organic Compound Synthesis:
Beyond its applications in agriculture and medicine, 2-CHLORO-4-TRIFLUOROMETHOXYPHENOL is also employed in the synthesis of other organic compounds for various industrial purposes. Its versatility in chemical reactions enables the production of a broad spectrum of specialty chemicals and materials.

InChI:InChI=1/C7H4ClF3O2/c8-5-3-4(1-2-6(5)12)13-7(9,10)11/h1-3,12H

Upstream product

• 659-28-9 p-trifluoromethoxybenzaldehyde 
• 828-27-3 4-Trifluoromethoxyphenol 

Downstream Products

• 2301866-59-9 N-3-pyridyl-N’-(1-[3-chloro-4-{2-chloro-4-(trifluoromethoxy)phenoxy}pyridine-2-yl]piperidin-4-yl)thiourea 
• 874571-72-9 1-[2-chloro-4-(trifluoromethoxy)phenyl]methanamine 
• 874482-94-7 2-chloro-4-(trifluoromethoxy)benzonitrile 
• 1309111-02-1 N-[1-cyano-1-methyl-2-(5-cyano-2-{2-chloro-4-trifluoromethoxy-phenoxy}-phenoxy)-ethyl]-4-trifluoromethoxybenzamide 
• 1309111-10-1 4-{2-chloro-4-trifluoromethoxy-phenoxy}-3-hydroxy-benzonitrile 
• 1309111-23-6 N-[1-cyano-1-methyl-2-(5-cyano-2-{2-chloro-4-trifluoromethoxy-phenoxy}-phenoxy)-ethyl]-4-trifluoromethylsulfonylbenzamide 
• 1309111-21-4 N-[1-cyano-1-methyl-2-(5-cyano-2-{2-chloro-4-trifluoromethoxy-phenoxy}-phenoxy)-ethyl]-4-trifluoromethylsulfanylbenzamide 
• 1309111-19-0 N-[(1R)-1-cyano-1-methyl-2-(5-cyano-2-{2-chloro-4-trifluoromethoxy-phenoxy}-phenoxy)-ethyl]-4-trifluoromethoxybenzamide 
• 1309111-17-8 N-[(1S)-1-cyano-1-methyl-2-(5-cyano-2-{2-chloro-4-trifluoromethoxy-phenoxy}-phenoxy)-ethyl]-4-trifluoromethoxybenzamide 
• 1228695-06-4 3-(2-amino-2-cyano-2-methyl-ethoxy)-4-(2-chloro-4-trifluoromethoxy-phenoxy)-benzonitrile 

Relevant academic research and scientific papers

Novel 2,3-dihydrobenzofuran-2-carboxylic acids: Highly potent and subtype-selective PPARα agonists with potent hypolipidemic activity

The design and synthesis of a novel class of 2,3-dihydrobenzofuran-2- carboxylic acids as highly potent and subtype-selective PPARα agonists are reported. Systematic study of structure-activity relationships has identified several key structural elements within this class for maintaining the potency and subtype selectivity. Select compounds were evaluated in animal models of dyslipidemia using Syrian hamsters and male Beagle dogs, and all these compounds displayed excellent cholesterol- and triglyceride-lowering activity at dose levels that were much lower than the marketed weak PPARα agonist fenofibrate.

(2R)-2-Methylchromane-2-carboxylic acids: Discovery of selective PPARα agonists as hypolipidemic agents

A SAR study was conducted on chromane-2-carboxylic acid toward selective PPARα agonisim. As a result, highly potent, and selective PPARα agonists were discovered. The optimized compound 43 exhibited robust lowering of total cholesterol levels in hamster and dog animal models.

Biguanide and dihydrotriazine derivatives

Biguanide and dihydrotriazine derivatives, preferably substituted asymmetrical imidodicarbonimidic diamides derived from hydroxylamines, and compositions containing biguanide and dihydrotriazine derivatives are disclosed. In addition, methods of using the

Carbamoylimidazole derivatives and fungicidal use thereof

Novel carbamoylimidazole derivatives of the formula (I) STR1 in which R1 represents lower alkyl, lower alkoxy-lower alkyl or cycloalkyl having 3 to 8 carbon atoms, R2 represents fluoro-substituted lower alkyl, X represents oxygen or sulfur, Y represents halogen or lower alkyl, m represents the numbers 0, 1 or 2, and n represents the numbers 2, 3, 4, 5 or 6, and the use of the new compounds as agricultural and horticultural fungicides.

Herbicidal ethers

Ethers, such as 2-[[4-[4-(trifluoromethoxy)phenoxy]phenoxy]]propanoic acid, methyl ester, useful for control of weeds.