70786-25-3

Usage

Uses

Used in Pharmaceutical Development:
(tetrazolo-5-yl)acetanilide is used as a potential anticonvulsant and analgesic agent for the treatment of various neurological conditions and pain management. Its unique chemical structure allows for the exploration of its effects on the central nervous system and its potential to alleviate seizures and pain.
Used in Organic Synthesis:
(tetrazolo-5-yl)acetanilide serves as a building block in organic synthesis, contributing to the development of new compounds with diverse applications. Its tetrazole ring provides a versatile platform for chemical modifications and the creation of novel molecules with potential uses in various industries.
Used in Material Science:
(tetrazolo-5-yl)acetanilide has been investigated for its potential in the synthesis of new materials, which could have applications in areas such as electronics, pharmaceuticals, and other advanced technologies. The unique properties of (tetrazolo-5-yl)acetanilide make it a promising candidate for the development of innovative materials with enhanced performance characteristics.

Upstream product

• 21743-75-9 (1H-tetrazol-5-yl)-acetic acid 
• 62-53-3 aniline 
• 13616-37-0 ethyl (tetrazol-5-yl)acetate 
• 621-03-4 cyanoacetanilide 
• 17846-68-3 tributyltin azide 

Downstream Products

• 7341-97-1 N-phenyl propynamide 

Relevant academic research and scientific papers

C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases

This invention is directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as to the use of such compositions in the treatment of patients su

The reaction of 2-(tetrazol-5-yl)alkyl ketones and of 2-(tetrazol-5-yl)alkanoic acid derivatives with lead tetraacetate. A novel method of preparation of alk-2-ynyl ketones and alk-2-ynoic acid derivatives

The majority of tetrazolylacetyl derivatives 2 and 7, when treated with lead tetraacetate in dry 1,4-dioxane at room or lower temperature, are oxidized with elimination of molecular nitrogen mainly to the corresponding alkynoyl derivatives 4 and 8, respectively. Vinylidenes (25) have been shown to be the intermediates of the reaction. The reaction does not take place when either the tetrazolyl group is N-substituted or the carbon atom separating the tetrazolyl and the carbonyl groups is disubstituted or these two groups are separated by two carbon atoms as in compound 17. The reaction offers a convenient method for the conversion of 2-cyanoacetyl derivatives into alk-2-ynoyl derivatives via intermediate tetrazolylacetyl derivatives. The 4-methoxyanilide 7o reacts differently, affording the fused heterocyclic compounds 19o and 20o.

C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases

This invention is directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as to the use of such compositions in the treatment of patients su