70804-02-3

Basic information

• Product Name: N-(2,2,6,6-tetramethyl-4-piperidyl)ethylenediamine
• Synonyms: N-(2,2,6,6-tetramethyl-4-piperidyl)ethylenediamine;N-(2,2,6,6-Tetramethyl-4-piperidinyl)-1,2-ethanediamine
• CAS NO: 70804-02-3
• Molecular Formula: C₁₁H₂₅N₃
• Molecular Weight: 199.3363
• EINECS: 274-903-5
• Mol File: 70804-02-3.mol

Chemical Properties

• Boiling Point: 263.5°C at 760 mmHg
• Flash Point: 130.6°C
• Appearance: /
• Density: 0.93g/cm³
• Vapor Pressure: 0.0102mmHg at 25°C
• Refractive Index: 1.494
• CAS DataBase Reference: N-(2,2,6,6-tetramethyl-4-piperidyl)ethylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,2,6,6-tetramethyl-4-piperidyl)ethylenediamine(70804-02-3)
• EPA Substance Registry System: N-(2,2,6,6-tetramethyl-4-piperidyl)ethylenediamine(70804-02-3)

Safety Data

• Hazardous Substances Data: 70804-02-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H25N3/c1-10(2)7-9(13-6-5-12)8-11(3,4)14-10/h9,13-14H,5-8,12H2,1-4H3

Relevant articles and documents

Synthesis and biological properties of N2-substituted spin-labeled analogues of actinomycin D.

We have synthesized N2-[4-(2,2,6,6-tetramethyl-1-piperidinyloxy)]actinomycin D And the related 1,2-diaminoethane and 1,3-diaminopropane derivatives and evaluated their biological properties. Binding studies with the spin-labeled actinomycin D analogues and DNA were carried out by using circular dichroism, electron spin resonance, and thermal denaturation. These studies have suggested that the derivatives bind to DNA and that their DNA-binding modes are similar but not identical. Spin-labeled actinomycin D derivatives were less potent in inhibiting Escherichia coli DNA-dependent RNA polymerase reaction than actinomycin D and were less toxic to L1210 cells in vitro than the parent compound. Spin-labeled actinomycin D derivatives were more common than the parent compounds against P-388 leukemia cells in vitro with little or no toxicity.