70842-93-2

Basic information

• Product Name: 2-{4-[(2E)-3-furan-3-ylprop-2-enoyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine
• Synonyms: (2E)-1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-3-(furan-3-yl)prop-2-en-1-one; 2-propen-1-one, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-3-(3-furanyl)-, (2E)-
• CAS NO: 70842-93-2
• Molecular Formula: C₂₁H₂₃N₅O₄
• Molecular Weight: 409.4384
• Mol File: 70842-93-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 696.8°C at 760 mmHg
• Flash Point: 375.2°C
• Density: 1.335g/cm³
• Vapor Pressure: 2.9E-19mmHg at 25°C
• Refractive Index: 1.666
• CAS DataBase Reference: 2-{4-[(2E)-3-furan-3-ylprop-2-enoyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[(2E)-3-furan-3-ylprop-2-enoyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine(70842-93-2)
• EPA Substance Registry System: 2-{4-[(2E)-3-furan-3-ylprop-2-enoyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine(70842-93-2)

Safety Data

• Hazardous Substances Data: 70842-93-2(Hazardous Substances Data)

Upstream product

• 23680-84-4 2-chloro-6,7-dimethoxyquinazolin-4-amine 
• 84050-21-5 4-amino-6,7-dimethoxy-2-(4-formylpiperazino)quinazoline hydrochloride 
• 39244-10-5 3-(furan-3-yl)prop-2-enoic acid 
• 84050-22-6 2-piperazinyl-4-amino-6,7-dimethoxyquinazoline hydrochloride 

Relevant articles and documents

Pyrimidine Derivatives. 4. Synthesis and Antihypertensive Activity of 4-Amino-2-(4-cinnamoylpiperazino)-6,7-dimethoxyquinazoline Derivatives

A series of 30 4-amino-2-(4-cinnamoylpiperazino)-6,7-dimethoxyquinazoline derivatives was prepared and tested for their ability to reduce blood pressure in conscious, spontaneously hypertensive rats (SHR).A number of these compounds, notably 4-amino-2-(4-