70871-52-2Relevant academic research and scientific papers
Generation and reaction of ammonium ylides in basic two-phase systems
Kowalkowska, Anna,Sucholbiak, Dorota,Jonczyk, Andrzej
, p. 925 - 933 (2007/10/03)
Reaction of the quaternary ammonium salts 2a-i with electrophilic alkenes 3, active alkylating agents 7 or aromatic aldehydes 11, carried out in basic two-phase systems A-D, afforded cyclopropanes 4, cyanoalkenes 8 or cyanooxiranes 12 respectively, via the corresponding ammonium ylides 2+-. The method is very simple, and gives cyclopropanes 4 and cyanoalkenes 8 in high yield. Under similar conditions, 1-cyanodienes 8aa,ba were cyclopropanated at the γ,δ-double bond with formation of vinylcyclopropanes 9a,b. The stereochemistry of the prepared cyclopropanes was elucidated from literature, 1H NMR spectroscopic data, NOE experiments or X-ray single crystal analysis. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.
A NEW SYNTHESIS OF POLYSUBSTITUTED CYCLOPROPANES
Yoneda, Ryuji,Santo, Kazunori,Harusawa, Shinya,Kurihara, Takushi
, p. 921 - 928 (2007/10/02)
Polysubsituted cyclopropane derivatives (3a-3h) could be obtained by reaction of activated olefinic compounds (2) with the cyanophosphates (1) of aldehydes (benzaldehyde, cinnamaldehyde and crotonaldehyde) in the presence of butyllithium and tetramethylet
