70872-38-7

Basic information

• Product Name: N-acetyl-N-methylphenylalanine methyl ester
• Synonyms: N-acetyl-N-methylphenylalanine methyl ester
• CAS NO: 70872-38-7
• Molecular Weight: 235.283
• Mol File: 70872-38-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-acetyl-N-methylphenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-acetyl-N-methylphenylalanine methyl ester(70872-38-7)
• EPA Substance Registry System: N-acetyl-N-methylphenylalanine methyl ester(70872-38-7)

Safety Data

• Hazardous Substances Data: 70872-38-7(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 3618-96-0 (S)-N-acetylphenylalanine 
• 70893-31-1 methyl (Z)-2-(N-methylacetamido)-3-phenylacrylate 
• 108-24-7 acetic anhydride 
• 24164-73-6 methyl (S)-2-(benzyloxycarbonyl-methyl-amino)-3-phenylpropionate 

Downstream Products

• 55260-07-6 N-methyl-N-acetyl-L-phenylalanine 

Relevant articles and documents

"One-pot" methylation of N-nosyl-α-amino acid methyl esters with diazomethane and their coupling to prepare N-methyl dipeptides

N-Nosyl-α-amino acid methyl esters are methylated quantitatively with diazomethane. After proper deprotection of the amino function by treatment with the reagent system mercaptoacetic acid/sodium methoxide, the obtained N-methyl amino acid methyl esters are coupled with N-Fmoe amino acid chlorides to afford the corresponding dipeptides. The obtained products do not show any detectable extent of racemization by 1H NMR and HPLC.

Novel formation and crystal structure of 2-(2,2,2-trifluoroethylidene)-6-trifluoro-methyl-2,3-dihydro-4H-1,4-oxazin-3- ones from N-acetyl-N-alkyl-α-amino acids

The title compounds (2a-g) were formed from N-acetyl-N-alkyl-α-amino acids (1a-g) on treatment with trifluoroacetic anhydride in the presence of pyridine. The structure of the product (2a) was determined by single crystal X-Ray analysis.