70880-60-3Relevant academic research and scientific papers
Karataviosides G-K, five new bisdesmosidic steroidal glycosides from the bulbs of Allium karataviense
Kuroda, Minpei,Ori, Kazutomo,Takayama, Hiroshi,Sakagami, Hiroshi,Mimaki, Yoshihiro
, p. 96 - 104 (2015/01/16)
We have analyzed the steroidal glycosides in Allium karataviense bulbs, and isolated five new bisdesmosidic steroidal glycosides: karataviosides G-K (1-5). The structures were elucidated by extensive spectroscopic analysis, including 2D NMR and enzymatic and hydrolytic cleavage. Karatavioside G (1) is an entirely novel furostanol glycoside, which has an O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranosyl unit at C-26 of the aglycone. Although a variety of cholestanol glycosides have been isolated, mainly from Liliaceae and Agavaceae, karataviosides J and K (4 and 5) are also notable because they are the most polar cholestanol bisdesmosides discovered, in which a lycotetraose is attached to C-3 of the aglycone, and a glucose or O-glucosyl-(1 → 3)-glucose is attached at C-16. The isolated glycosides were also evaluated for their cytotoxic activities against cultured tumor cell lines.
STEROID SAPONINS AND SAPOGENINS OF Allium. THE STRUCTURE OF KARATAVIOSIDE B
Bollerner, Yu. S.,Abdullaev, N. D.,Gorovits, M. B.,Abubakirov, N. K.
, p. 186 - 190 (2007/10/02)
A new glycoside of the spirostan series - karatavioside B (I) - has been isolated from an ethanolic extract of the inflorescences of Allium karataviense Rgl. (family Liliaceae).On the basis of chemical transformations and spectral characteristics the structure of (I) has been established as 25(R)-spirost-5-ene-2α,3β-diol S-O--(1-3)>--O-β-D-glucopyranosyl-(1-4)-β-D-galactopyranoside>.
