70883-30-6

Usage

General Description

The chemical 2-[(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetyl]-N-phenylhydrazinecarbothioamide is a complex organic compound with a long and specific name. It contains a purine ring and a carbothioamide functional group, and is composed of various carbon, hydrogen, nitrogen, and oxygen atoms. This chemical is likely to have pharmaceutical properties, potentially serving as a drug or medication due to its complex structure. Its specific use and potential effects would require further research and analysis.

Upstream product

• 7029-96-1 ethyl 2-(1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)acetate 
• 41838-25-9 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetohydrazide 
• 103-72-0 phenyl isothiocyanate 
• 58-55-9 theophylline 

Downstream Products

• 70863-01-3 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-(phenyl)thiazolidin-4-one 
• 1463829-92-6 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(4-chlorobenzyliden)thiazolidin-4-one 
• 1463829-97-1 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(4-bromobenzyliden)thiazolidin-4-one 
• 1463830-02-5 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(4-hydroxybenzyliden)thiazolidin-4-one 
• 1463830-07-0 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(4-N-dimethylaminobenzyliden)thiazolidin-4-one 
• 1463829-85-7 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(4-fluorobenzyliden)thiazolidin-4-one 
• 1463829-78-8 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(benzyliden)thiazolidin-4-one 
• 1463830-13-8 2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-phenyl-5-(2-nitrobenzyliden)thiazolidin-4-one 

Relevant academic research and scientific papers

Synthesis and hypoglycemic activity of some new theophylline derivatives

Thirty-one new theophylline derivatives have been synthesized and evaluated for their hypoglycemic activity. Compounds 24 (56% reduction) and 31 (57% reduction) showed better hypoglycemic activity than the standard drug glibenclamide which showed 52% redu

The synthesis and the biological evaluation of new thiazolidin-4-one derivatives containing a xanthine moiety

Starting from theophylline (1,3-dimethylxanthine) new thiazolidin-4-one derivatives 7a1-7, 7b1-7 have been synthesized as potential antidiabetic drugs. The structure of the new derivatives was confirmed using spectral methods (FT-IR, 1H-NMR, 13C-NMR). The in vitro antioxidant potential of the synthesized compounds was evaluated according to the ferric reducing power, the total antioxidant activity and the DPPH and ABTS radical scavenging assays. Reactive oxygen species (ROS) and free radicals are considered to be implicated in a variety of pathological events, such as diabetes mellitus and its micro- and macrovascular complications. The results of chemical modulation of the thiazolidin-4-one intermediaries 6a, 6b through condensation with several aromatic aldehydes is the improvement of the antioxidant effect. All benzylidenethiazolidin-4-one derivatives 7a 1-7, 7b1-7 are more active than their parent thiazolidin-4-ones. The most active compounds are the ones obtained by reaction of condensation with 4-hydroxybenzaldehyde (compounds 7a5, 7a 6), 4-dimethylaminobenzaldehyde (compounds 7a6, 7b 6) and 2-nitrobenzaldehyde (compounds 7a7, 7b 7).