709032-01-9Relevant academic research and scientific papers
Diastereo- and enantioselective synthesis of a conagenin skeletal amide moiety
Rodrigues, J. Augusto R.,Moran, Paulo J.S.,Milagre, Cíntia D.F.,Ursini, Cleber V.
, p. 3579 - 3582 (2004)
A synthetic study was carried out to obtain epimers of a protected 2,4-dihydroxy-3-methylpentanoic ester 9, which is a central building block of the immunomodulator (+)-conagenin 1. The configuration of the three contiguous stereogenic centers was determined by NMR measurements and comparison with the stereogenic centers of lactone 10.
