70912-51-5

Upstream product

• 64-17-5 ethanol 
• 70912-54-8 5-azepan-2-ylidene-2,2-dimethyl-[1,3]dioxane-4,6-dione 
• 99054-17-8 ethyl 8-azido-3-oxooctanoate 
• 3338-03-2 2-methyl-4,5,6,7-tetrahydro-3H-azepine 
• 105-58-8 Diethyl carbonate 
• 848771-93-7 methyl 3-[(2E)-2-(2-ethoxy-2-oxoethylidene)azepan-1-yl]propanoate 
• 105-60-2 caprolactam 
• 7203-96-5 1-azacycloheptane-2-thione 
• 125627-72-7 3-(2-Thioxo-azepan-1-yl)-propionic acid methyl ester 
• 487040-24-4 ethyl 8-bromo-3-oxooctanoate 
• 666706-61-2 ethyl 3-oxo-2,2,8-tribromooctanoate 
• 99054-05-4 ethyl 8-chloro-3-oxo-octanoate 

Downstream Products

• 340020-38-4 ethyl 2-hydroxy-4-oxo-4,6,7,8,9,10-hexahydropyrido[1,2-a]azepine-1-carboxylate 
• 164366-30-7 ethyl 4-oxo-4,6,7,8,9,10-hexahydropyrido[1,2-a]azepine-1-carboxylate 
• 1006381-20-9 C₁₉H₂₃NO₂ 

Relevant academic research and scientific papers

Silver-catalyzed hydroamination: Synthesis of N-bridgehead pyrroles, incorporating a protection-deprotection strategy for preparation of cyclic secondary vinylogous carbamates

N-Bridgehead pyrroles are efficiently prepared from cyclic secondary vinylogous carbamates using a two-step sequence. This sequence involves C-propargylation followed by a silver-catalyzed intramolecular hydroamination. Hydroamination is brought about using microwave irradiation and affords the desired N-bridgehead pyrroles rapidly and in good yield. Cyclic secondary vinylogous carbamates are prepared using a mild, economical procedure. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.

A Direct Retro-Reformatsky Fragmentation: Formal Ring Enlargement of Cyclic Ketones for Novel and Practical Synthesis of Heterocyclic Enamines

A novel and practical synthesis of heterocyclic enamines has been developed from the formal ring enlargement of cyclic ketones, which comprised the retro-Reformatsky fragmentation reaction as a key step. Under alkaline bromination conditions, the Reformat

A versatile route to β-enamino esters by acylation of lithium enamines with diethyl carbonate or benzyl chloroformate

A versatile route to β-enamino esters 1, using accessible starting materials, was developed. Lithiated enamines are allowed to react with diethyl carbonate or benzyl chloroformate with the formation of the β-enamino esters 1a or 1b. The reaction is rather general from a wide array of ketimines and aldimines. Products included cyclic β-enamino esters 1aa-ac, very useful for the synthesis of natural products.

Application of the Intramolecular Aza-Wittig Reaction to the Synthesis of Vinylogous Urethanes and Amides

The treatment of ω-azido β-dicarbonyl derivatives with 1 equiv of triphenylphosphine leads to a transient phosphinimine (Staudinger reaction), which cyclizes into vinylogous urethanes and amides via an intramolecular aza-Wittig reaction in excellent yields.The starting azides were obtained by a nucleophilic substitution by NaN3 in Me2SO on the corresponding ω-halo β-dicarbonyl derivatives that were accessible by the γ-alkylation of β-dicarbonyl compounds with α,ω-dihaloalkanes.

Thermolyse des β-enaminodiesters cycliques : acces a divers β-enaminoesters, β-enamino-thioesters et β-enaminoamides

A new synthesis of β-enaminoesters, β-enaminothioesters et β-enaminoamides by thermic decomposition of β-enaminodiesters is described.