70919-47-0

Basic information

• Product Name: (2R)-exo-norbornyl (R)-α-methoxy-α-trifluoromethylphenylacetate
• Synonyms: (2R)-exo-norbornyl (R)-α-methoxy-α-trifluoromethylphenylacetate
• CAS NO: 70919-47-0
• Molecular Weight: 328.331
• Mol File: 70919-47-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R)-exo-norbornyl (R)-α-methoxy-α-trifluoromethylphenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-exo-norbornyl (R)-α-methoxy-α-trifluoromethylphenylacetate(70919-47-0)
• EPA Substance Registry System: (2R)-exo-norbornyl (R)-α-methoxy-α-trifluoromethylphenylacetate(70919-47-0)

Safety Data

• Hazardous Substances Data: 70919-47-0(Hazardous Substances Data)

Upstream product

• 497-37-0 (2R)-(+)-exo-2-norborneol 
• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 28627-78-3 2-endo-norbornyl metanesulfonate 
• 61277-90-5 exo-norborneol 
• 497-36-9 endo-norborneol 

Relevant articles and documents

Synthesis of enantiomers of exo-2-norbornyl-N-n-butylcarbamate and endo-2-norbornyl-N-n-butylcarbamate for stereoselective inhibition of acetylcholinesterase

The acetylcholinesterase inhibition by enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates shows high stereoselelectivity. For the acetylcholinesterase inhibitions by (R)-(+)- and (S)-(-)-exo-2-norbornyl-N-n- butylcarbamates, the R-enantiomer is more potent than the S-enantiomer. But, for the acetylcholinesterase inhibitions by (R)-(+)- and (S)-(-)-endo-2-norbornyl- N-n-butylcarbamates, the S-enantiomer is more potent than the R-enantiomer. Optically pure (R)-(+)-exo-, (S)-(-)-exo-, (R)-(+)-endo-, and (S)-(-)-endo-2-norbornyl-N-n-butylcarbamates are synthesized from condensations of optically pure (R)-(+)-exo-, (S)-(-)-exo-, (R)-(+)-endo-, and (S)-(-)-endo-2-norborneols with n-butyl isocyanate, respectively. Optically pure norborneols are obtained from kinetic resolutions of their racemic esters by lipase catalysis in organic solvent.