70920-08-0

Basic information

• Product Name: N-[(morpholin-4-ylmethyl)carbamoyl]pyridine-3-carboxamide
• CAS NO: 70920-08-0
• Molecular Formula: C₁₂H₁₆N₄O₃
• Molecular Weight: 264.2804
• Mol File: 70920-08-0.mol
• Article Data: 1

Chemical Properties

• Density: 1.258g/cm³
• Refractive Index: 1.559
• CAS DataBase Reference: N-[(morpholin-4-ylmethyl)carbamoyl]pyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(morpholin-4-ylmethyl)carbamoyl]pyridine-3-carboxamide(70920-08-0)
• EPA Substance Registry System: N-[(morpholin-4-ylmethyl)carbamoyl]pyridine-3-carboxamide(70920-08-0)

Safety Data

• Hazardous Substances Data: 70920-08-0(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 50-00-0 formaldehyd 
• 3298-38-2 3-allophanoylpyridine 
• 20260-53-1 pyridine-3-carbonyl chloride hydrochloride 

Relevant articles and documents

Synthesis and pharmacological evaluation of N'-morpholinomethylurea derivatives with platelet antiaggregant activity

In the attempt to prolong and stabilize the known antiaggregant activity of morpholinomethylurea (MMU) derivatives were prepared with carboxylic acids possessing antiaggregant, antiinflammatory or hypolipemic activity. The results of the experiments showed the important anti-aggregant and hypolipemic activity of N-2(p-chlorophenoxy)-isobutyryl-N'-morpholinomethylurea (plafibride, ITA 104). The results obtained seem to indicate that the activity of these new N-acyl-N'-MMU is due initially to the molecule per se although it cannot be totally ruled out that part of the pharmacodynamic effect of the MMU may depend on a prodrug-like behaviour.