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1-(3-fluoro-8-isopropyl-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine is a complex organic compound with a molecular formula of C21H24FN2S. It is a derivative of dibenzo[b,f]thiepin, a tricyclic structure that includes a benzene ring fused to a thiophene ring. The compound features a fluorine atom at the 3-position, an isopropyl group at the 8-position, and a piperazine ring attached at the 1-position. The 10,11-dihydro indicates the presence of two hydrogen atoms that have reduced the aromaticity of the dibenzo[b,f]thiepin core, making it partially saturated. 1-(3-fluoro-8-isopropyl-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine is known for its potential applications in the field of pharmaceuticals, particularly as a serotonin receptor agonist, and has been studied for its effects on the central nervous system. Its chemical structure and properties make it a subject of interest for researchers exploring new therapeutic agents.

70931-22-5

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70931-22-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 70931-22-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,9,3 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 70931-22:
(7*7)+(6*0)+(5*9)+(4*3)+(3*1)+(2*2)+(1*2)=115
115 % 10 = 5
So 70931-22-5 is a valid CAS Registry Number.

70931-22-5Relevant academic research and scientific papers

FLUORINATED TRICYCLIC NEUROLEPTICS WITH PROLONGED ACTION: 7-FLUORO-11--2-ISOPROPYL-10,11-DIHYDRODIBENZOTHIEPIN

Protiva, Miroslav,Jilek, Jiri,Rajsner, Miroslav,Pomykacek, Josef,Ryska, Miroslav,et al.

, p. 698 - 722 (2007/10/02)

Substitution reaction of 11-chloro-7-fluoro-2-isopropyl-10,11-dihydrodibenzothiepin with 1-(2-hydroxyethyl)piperazine gave the title compound I which proved a very potent and long acting oral neuroleptic agent ("isofloxythepin").Its resolution by means of dibenzoyl-(+)- and (-)-tartaric acid led to (-)- and (+)-enantiomer out of which the former represents the neuroleptically active component.In the synthetic sequence leading to I, preparation of two key intermediates was re-elaborated using new partial sequences: 4-fluoro-2-iodobenzoic acid (XIII) from 4-fluoro-2-nitroaniline (V) via the nitrile VI and the acids VIII and XII, and acetic acid (XVIII) from XIII via XIV and the compounds XV-XVII.The sulfoxides and N-oxides XIX-XXII were prepared as potential metabolites of isofloxithepin (I).

3 Fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(bf) thiepins and method for the preparation thereof

-

, (2008/06/13)

Techniques for the preparation of 3-fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(b,f) thiepins and their addition salts with organic and inorganic acids are disclosed. The described compositions evidence psychotropic activity and low toxicity and are characterized as neuroliptics with a high degree of cataleptic, anti-apomorphine and central depressant action.

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