709633-52-3Relevant academic research and scientific papers
An efficient synthesis of 2-Alkylthio-5-phenylmethylidene-4H-imidazolin-4-ones
Ding, Ming-Wu,Sun, Yong,Liu, Zhao-Jie
, p. 1267 - 1274 (2007/10/03)
2-Alkylthio-5-phenylmethylidene-4H-imidazolin-4-ones 5 were synthesized by S-alkylation of thioimidazolinones 4, which were obtained via cyclization of carbodiimides 2 with Na2S/HOAc. The direct reaction of carbodiimides 2 with butylthiol could not give 2-butylthio-4H-imidazolin-4-ones 3.
Synthesis and biological evaluation of C-3′NH/C-10 and C-2/C-10 modified paclitaxel analogues
Baloglu, Erkan,Hoch, Jeannine M.,Chatterjee, Sabarni K.,Ravindra, Rudravajhala,Bane, Susan,Kingston, David G. I.
, p. 1557 - 1568 (2007/10/03)
Concurrent modifications on the C-3′NH/C-10, and C-2/C-10 positions on paclitaxel were carried out as a way of investigating possible synergistic effects. The biological activities of these analogues were evaluated in both a microtubule assembly assay and
