70971-69-6Relevant academic research and scientific papers
Synthesis of acyl pyrroles via palladium-catalyzed carbonylative amination of aryl and alkenyl iodides
Ho, Stephanie,Bondarenko, Ganna,Rosa, David,Dragisic, Bojan,Orellana, Arturo
experimental part, p. 2008 - 2012 (2012/04/17)
A palladium-catalyzed synthesis of acyl pyrroles from aryl and alkenyl iodides is reported. This carbonylative amination requires only atmospheric (balloon) pressure of carbon monoxide and proceeds with Pd(PPh3) 4 and Pd-NHC catalyst
A convenient synthesis of N-acylpyrroles from primary aromatic amides
Ekkati, Anil R.,Bates, Dallas K.
, p. 1959 - 1961 (2007/10/03)
Synthesis of N-acylpyrroles in 45-85% isolated yield from primary aromatic amides and excess 2,5-dimethoxytetrahydrofuran in presence of one equivalent of thionyl chloride is reported. This method has several advantages including short reaction times, mild reaction conditions, and easy workup. The technique works particularly well for deactivated aromatic amides.
