71007-15-3Relevant academic research and scientific papers
Intermolecular Multiple Dehydrogenative Cross-Couplings of Ketones with Boronic Acids and Amines via Copper Catalysis
Wang, Tianzhang,Chen, Guowei,Lu, Yu-Jing,Chen, Qian,Huo, Yanping,Li, Xianwei
supporting information, p. 3886 - 3892 (2019/07/19)
An efficient and versatile oxidative coupling reaction was developed for the synthesis of valuable β-functionalized unsaturated ketones and meta-substituted phenols. In the case of intramolecular reactions, achieving rapid molecular complexity through multiple dehydrogenative couplings is already a well-established strategy. Herein, we report an intermolecular multiple dehydrogenative coupling between ketones and nucleophilic amines or boronic acids using inexpensive copper(I) oxide as a catalyst. This method provides a facile access to highly desirable chemical products such as α,β-unsaturated ketones, enaminones, and synthetically relevant meta-substituted phenols. (Figure presented.).
ENAMINE CHEMISTRY-XIX PREPARATION AND ALKYLATION OF CYCLIC AND NON-CYCLIC ENAMINO-THIONES
Rasmussen, J. B.,Shabana, R.,Lawesson, S.-O.
, p. 197 - 202 (2007/10/02)
Enamino-thiones of the general type ArC(S)CH:CHNR2, 3 (Ar = phenyl, p-methoxyphenyl and p-bromophenyl, NR2 = pyrrolidinyl, piperidino), were prepared by reacting the corresponding enaminones, 2, with 2,4-bis-(4-methoxyphenyl)-1,3,2,4
