71018-33-2

Upstream product

• 201230-82-2 carbon monoxide 
• 1504-55-8 (E)-3-phenyl-2-methyl-2-propenol 
• 110969-20-5 bromophenylacetaldehyde allyl ethyl acetal 

Relevant academic research and scientific papers

The First Stereoselective Palladium-Catalyzed Cyclocarbonylation of β,γ-Substituted Allylic Alcohols

β,γ-Substituted allylic alcohols react with CO in the presence of catalytic quantities of palladium acetate and 1,4-bis(diphenylphosphino)butane affording α,β-substituted-γ-butyrolactones in 42-85% isolated yields. The complete stereoselectivity observed

General Synthetic Route to γ-Butyrolactones via Stereoselective Radical Cyclization by Organotin Species

A new method for the preparation of γ-butyrolactones is described in which the key step is the highly stereoselective radical cyclization of bromoacetals to 2-alkoxytetrahydrofurans in the presence of polymeric or low-molecular weight organotin species. 2-Alkoxytetrahydrofurans can be easily converted into γ-butyrolactones by Jones oxidation.