710311-29-8Relevant academic research and scientific papers
Synthesis and characterizations of novel quinoline derivatives having mixed ligand activities at the κ and μ receptors: Potential therapeutic efficacy against morphine dependence
Deb, Ishani,Paira, Priyankar,Hazra, Abhijit,Banerjee, Sukdeb,Dutta, Pradip Kumar,Mondal, Nirup Bikash,Das, Sumantra
experimental part, p. 5782 - 5790 (2009/12/28)
Based on an established 3D pharmacophore, a series of quinoline derivatives were synthesized. The opioidergic properties of these compounds were determined by a competitive binding assay using 125I-Dynorphine, 3H-DAMGO and 125/
