710313-36-3

Upstream product

• 710313-33-0 (2S,3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-5-isopropenyl-2-methyl-cyclohexanone 
• 127853-80-9 (2S,3S,5S)-3-Hydroxy-2-methyl-5-(1-methylethenyl)cyclohexanone 
• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 710313-29-4 tert-Butyl-((1S,2R,5S)-5-isopropenyl-2-methyl-cyclohex-3-enyloxy)-diphenyl-silane 

Downstream Products

• 710313-28-3 (1S,2R,3S,4S,6S)-2-(tert-Butyl-dimethyl-silanyloxy)-4-(tert-butyl-diphenyl-silanyloxy)-3-methyl-6-(2-methyl-oxiranyl)-cyclohexanol 

Relevant academic research and scientific papers

Synthetic studies of the HIV-1 protease inhibitive didemnaketals: Stereocontrolled synthesis of an ester side chain

The stereocontrolled synthesis of the C1-C8 portion, the ester side chain of the HIV-1 protease inhibitive didemnaketals from the ascidian Didemnum sp., has been carried out through 15 steps starting from (S)-carvone as the chiral template. This approach involved the diastereoselective construction of three conjoint chiral centers by intramolecular chiral inducement, and generation of allylic alcohol intermediate through a key Grob fragmentation reaction.