710348-58-6

Basic information

• Product Name: (4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid
• Synonyms: (4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid
• CAS NO: 710348-58-6
• Molecular Weight: 249.118
• Mol File: 710348-58-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid(710348-58-6)
• EPA Substance Registry System: (4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid(710348-58-6)

Safety Data

• Hazardous Substances Data: 710348-58-6(Hazardous Substances Data)

Usage

General Description

(4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid is a chemical compound that contains a boronic acid group attached to a phenyl ring, which in turn is connected to a piperidine group. It is commonly used in organic synthesis and medicinal chemistry as a building block for the construction of larger molecules with potential biological activity. Boronic acids are known for their ability to react with and bind to certain classes of biomolecules, such as sugars and amino acids, making them valuable tools for the development of new drugs and chemical probes. The presence of the piperidine group in this compound may also make it useful for targeted delivery of drugs to specific tissues or cells in the body. Overall, (4-(2-(piperidin-1-yl)ethoxy)phenyl)boronic acid is a versatile and potentially valuable chemical for research and development in the pharmaceutical and biotechnology industries.

Upstream product

• 2008-75-5 N-chloroethylpiperidine hydrochloride 
• 269409-70-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 
• 836-58-8 1-[2-(4-bromophenoxy)ethyl]piperidine 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 767282-89-3 C₂₃H₂₆N₆O₂ 
• 1427186-59-1 (E)-1-(2-(4-(2-fluoro-1,2-diphenylvinyl)phenoxy)ethyl)piperidine 

Relevant articles and documents

Controlled Single and Double Iodofluorination of Alkynes with DIH- and HF-Based Reagents

A novel protocol for the regio- and stereoselective iodofluorination of internal and terminal alkynes using 1,3-diiodo-5,5,-dimethylhydantoin and HF-based reagents is disclosed. This approach is used to prepare a fluorinated tamoxifen derivative in two steps from commercially available starting materials. A facile method enabling controlled regioselective double iodofluorination of terminal alkynes is also presented.

OXAZOLE TYROSINE KINASE INHIBITORS

The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1 : provided that the sum of a and b is 0 or 1; T is O or NH Ar1 is a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S, and being optionally substituted by one or more substituents R1; Ar2 Js a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S and being optionally substituted by one or more substituents R2; and R1 and R2are as defined in the claims. The compounds are inhibitors of kinases and in particular FLT3, FLT4 and Aurora kinases.