710349-35-2

Upstream product

• 274925-96-1 1-(4-benzyloxy-3-methoxyphenyl)-2-phenyl-ethanone 
• 74-88-4 methyl iodide 

Downstream Products

• 710349-73-8 1-(3,4-dihydroxy-5-nitro-phenyl)-2-methyl-2-phenyl-propan-1-one 
• 710349-72-7 1-(4-hydroxy-3-methoxy-5-nitro-phenyl)-2-methyl-2-phenyl-propan-1-one 
• 710349-71-6 1-(4-hydroxy-3-methoxy-phenyl)-2-methyl-2-phenyl-propan-1-one 

Relevant academic research and scientific papers

Synthesis of 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl-ethanone and derivatives as potent and long-acting peripheral inhibitors of catechol-O-methyltransferase

A homologous series of novel nitro-catechol structures (7a-7e) were synthesized and tested as inhibitors of the enzyme catechol-O-methyltransferase (COMT). Increasing chain length was found to have significant impact on both brain penetration and duration